Abstract

A.
SPECIFIC AIMS The function of this Administration Core is to provide the UCACE with the organizational, administrative and secretarial support to enable the translational research goals of the program to be accomplished. Specific responsibilities of this core, embodied within the UCACE office are as follows: 1. Coordinate the scientific activities of the program. 2. Coordinate and oversee the educational program of the UCACE 3. Oversee regulatory documentation related to any research performed on humans. 4. Facilitate formal and informal interactions between investigators. 5. Coordinate the visits of the External Scientific Advisory Board, including mini-symposia. 6. Prepare annual progress reports. 7. Organize visits of other external scientists and consultants. 8. Provide day-to-day administrative (fiscal and secretarial) support to investigators. 9. Organize and administer monthly UCACE Research Seminars. 10. Keep accurate records and accounts on resource utilization. 11. Arrange for travel of Director and Associate Director to ACE meetings. Support services will be provided to all projects, pilots and other UCACE activities to ensure their success

Public Health Relevance

The University of Chicago Autoimmunity Center of Excellence (UCACE) Administrative Core will provide the administrative support to the Director and investigators necessary for them successfully complete the research and educational goals of the Center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI082724-07
Application #
8842921
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2015-06-01
Budget End
2016-05-31
Support Year
7
Fiscal Year
2015
Total Cost
Indirect Cost

  Institution

Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637

  Publications

Kinloch, Andrew J; Kaiser, Ylva; Wolfgeher, Don et al. (2018) In Situ Humoral Immunity to Vimentin in HLA-DRB1*03+ Patients With Pulmonary Sarcoidosis. Front Immunol 9:1516
Chen, Yao-Qing; Wohlbold, Teddy John; Zheng, Nai-Ying et al. (2018) Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies. Cell 173:417-429.e10
Henry, Carole; Palm, Anna-Karin E; Krammer, Florian et al. (2018) From Original Antigenic Sin to the Universal Influenza Virus Vaccine. Trends Immunol 39:70-79
Wilson, Patrick C; Cobey, Sarah (2018) Characterization of the immunologic repertoire: A quick start guide. Immunol Rev 284:5-8
Stamper, Christopher T; Wilson, Patrick C (2018) What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Is Affinity Maturation a Self-Defeating Process for Eliciting Broad Protection? Cold Spring Harb Perspect Biol 10:
DiPiazza, Anthony; Nogales, Aitor; Poulton, Nicholas et al. (2017) Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo. Sci Rep 7:10857
Lau, Denise; Lan, Linda Yu-Ling; Andrews, Sarah F et al. (2017) Low CD21 expression defines a population of recent germinal center graduates primed for plasma cell differentiation. Sci Immunol 2:
Bunker, Jeffrey J; Erickson, Steven A; Flynn, Theodore M et al. (2017) Natural polyreactive IgA antibodies coat the intestinal microbiota. Science 358:
Rivas, Jacqueline R; Ireland, Sara J; Chkheidze, Rati et al. (2017) Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients. Acta Neuropathol 133:43-60
Zost, Seth J; Parkhouse, Kaela; Gumina, Megan E et al. (2017) Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains. Proc Natl Acad Sci U S A 114:12578-12583

Showing the most recent 10 out of 51 publications