The Biostatistics and Bioinformatics Core (BBC) provides support with design, data management and analysis of research studies for the University of New Mexico Interdisciplinary HPV Prevention Center (UNMIHPC). Moreover, it serves as a centralized resource for biostatistical consulting and analyses for all scientific projects proposed by the UNM-IHPC. The unit provides a centralized base to each of the four scientific research projects at all levels of investigation, beginning with the formulation of more specific hypotheses related to the overall unifying hypotheses, reviewing the design of studies, and evaluating the utility of measurement techniques. Support and consultation concludes with aiding in the interpretation, presentation, and final writing of results. The BBC also serves to warehouse and maintain a public health population-based data resource the New Mexico HPV Pap Registry (NMHPVPR), which under New Mexico Administrative code collects retrospective and longitudinal data from state-wide, regional and national laboratories on all cervical screening, diagnostic and treatment procedures. The BBC will promote the UNMIHPC research aims as follows: 1) finalize the study designs and protocols in collaboration with each of the study investigators;2) collaborate with the study investigators in the development of the forms and applications for recording data;3) assist in development of protocols for data transmission;4) collaborate with the study investigators in developing detailed Manuals of Procedures;5) develop and manage the IHPC central and project-specific relational databases including the NMHPVPR;6) run SAS quality-control program checks;7) maintain a Master Database for each project with appropriate backups and security checks;8) monitor study progress and distribute monthly study reports;9) produce reports summarizing the status of data acquisition by subject, distributions and summary statistics for the primary variables;10) interface and perform linkages to the New Mexico state-wide immunization information system (NM-SIIS); 11) perform basic and complex statistical analyses for the scientific projects as needed;and 12) develop and maintain the IHPC web site in collaboration with the UNM Health Sciences Center (UNM-HSC) web master.

Public Health Relevance

The University of New Mexico Interdisciplinary STI Prevention Center will focus on the most common sexually transmitted agents, human papillomavirus (HPV) infections. To maximally realize improvements in HPV prevention, the Center will partner basic biological discovery, technological advancements, populationbased effectiveness and diffusion of interventions across laboratory, clinical &real-worid settings.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI084081-04
Application #
8382468
Study Section
Special Emphasis Panel (ZAI1-MMT-M)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
4
Fiscal Year
2012
Total Cost
$586,092
Indirect Cost
$189,757
Name
University of New Mexico Health Sciences Center
Department
Type
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Arrossi, Silvina; Temin, Sarah; Garland, Suzanne et al. (2017) Primary Prevention of Cervical Cancer: American Society of Clinical Oncology Resource-Stratified Guideline. J Glob Oncol 3:611-634
Dareng, E O; Ma, B; Famooto, A O et al. (2016) Prevalent high-risk HPV infection and vaginal microbiota in Nigerian women. Epidemiol Infect 144:123-37
Joste, Nancy E; Ronnett, Brigitte M; Hunt, William C et al. (2015) Human papillomavirus genotype-specific prevalence across the continuum of cervical neoplasia and cancer. Cancer Epidemiol Biomarkers Prev 24:230-40
Cuzick, Jack; Myers, Orrin; Hunt, William C et al. (2015) Human papillomavirus testing 2007-2012: co-testing and triage utilization and impact on subsequent clinical management. Int J Cancer 136:2854-63
Stoler, Mark H; Ronnett, Brigitte M; Joste, Nancy E et al. (2015) The Interpretive Variability of Cervical Biopsies and Its Relationship to HPV Status. Am J Surg Pathol 39:729-36
Starling, Randall; Nodulman, Jessica A; Kong, Alberta S et al. (2015) Usability Testing of an HPV Information Website for Parents and Adolescents. Online J Commun Media Technol 5:184-203
Nodulman, Jessica A; Starling, Randall; Kong, Alberta S et al. (2015) Investigating stakeholder attitudes and opinions on school-based human papillomavirus vaccination programs. J Sch Health 85:289-98
Tumban, Ebenezer; Muttil, Pavan; Escobar, Carolina Andrea A et al. (2015) Preclinical refinements of a broadly protective VLP-based HPV vaccine targeting the minor capsid protein, L2. Vaccine 33:3346-53
Yang, Zihua; Cuzick, Jack; Hunt, William C et al. (2014) Concurrence of multiple human papillomavirus infections in a large US population-based cohort. Am J Epidemiol 180:1066-75
Castle, Philip E; Hunt, William C; Langsfeld, Erika et al. (2014) Three-year risk of cervical precancer and cancer after the detection of low-risk human papillomavirus genotypes targeted by a commercial test. Obstet Gynecol 123:49-56

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