? Administrative Core B, Ravetch The Administrative Core will provide overall management of the administrative functions of the CCHI. This includes proving clear and regular communication channels between the CCHI participants, the NIH, and the External Scientific Advisory Group, reporting research findings annually and through publications, allocating research resources between the projects and the core, and ensuring compliance on animal and human subjects usage. The goals of the Administrative Core are 1) to provide scientific leadership and management for the Center; 2) maintain regulatory and fiscal compliance and administrative oversight; and 3) coordinate communications and research dissemination. The result of the execution of these goals will be a Center with synergized research projects, streamlined and accurate reporting, and vast public dissemination. Deliverables from the Administrative Core will include quarterly seminars and annual Distinguished Investigator lectures, a CCHI-specific website with both public and private access, annual progress reports to the NIAID following NIH policy and guidelines, multiple publications resulting from CCHI research, and data input to the ImmPort system.
| Keeffe, Jennifer R; Van Rompay, Koen K A; Olsen, Priscilla C et al. (2018) A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Rep 25:1385-1394.e7 |
| Wu, Xianfang; Dao Thi, Viet Loan; Huang, Yumin et al. (2018) Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell 172:423-438.e25 |
| Hernandez, Nicholas; Melki, Isabelle; Jing, Huie et al. (2018) Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency. J Exp Med 215:2567-2585 |
| Rosenberg, Brad R; Freije, Catherine A; Imanaka, Naoko et al. (2018) Genetic Variation at IFNL4 Influences Extrahepatic Interferon-Stimulated Gene Expression in Chronic HCV Patients. J Infect Dis 217:650-655 |
| Wang, Taia T; Bournazos, Stylianos; Ravetch, Jeffrey V (2018) Immunological responses to influenza vaccination: lessons for improving vaccine efficacy. Curr Opin Immunol 53:124-129 |
| Kenney, Adam D; Dowdle, James A; Bozzacco, Leonia et al. (2017) Human Genetic Determinants of Viral Diseases. Annu Rev Genet 51:241-263 |
| Bournazos, Stylianos; Ravetch, Jeffrey V (2017) Fc? Receptor Function and the Design of Vaccination Strategies. Immunity 47:224-233 |
| Robbiani, Davide F; Bozzacco, Leonia; Keeffe, Jennifer R et al. (2017) Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell 169:597-609.e11 |
| Wang, Taia T; Sewatanon, Jaturong; Memoli, Matthew J et al. (2017) IgG antibodies to dengue enhanced for Fc?RIIIA binding determine disease severity. Science 355:395-398 |
| Maamary, Jad; Wang, Taia T; Tan, Gene S et al. (2017) Increasing the breadth and potency of response to the seasonal influenza virus vaccine by immune complex immunization. Proc Natl Acad Sci U S A 114:10172-10177 |
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