Abstract

The Administrative Core will provide the infrastructure for the overall management and co-ordination of the Modeling Immunity for Biodefense Center at Emory University. At Emory the Administrative Core will facilitate and promote communication and interaction among the investigators and facilitate access to the obtained data and developed software packages. Provide fiscal/scientific oversight, review and consolidate yearly progress reports sent to the NIH Implement recommendations made by the External Scientific Advisory Group; and resolve all or any potential conflicts that might arise within and outside of the program. The Administrative Core will also be central in organizing workshops and symposiums.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI117891-01
Application #
8895034
Study Section
Special Emphasis Panel (ZAI1-QV-I (J3))
Project Start
Project End
Budget Start
2015-04-01
Budget End
2016-03-31
Support Year
1
Fiscal Year
2015
Total Cost
$71,882
Indirect Cost
$21,882

  Institution

Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322

  Publications

Lee, Juhye M; Huddleston, John; Doud, Michael B et al. (2018) Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants. Proc Natl Acad Sci U S A 115:E8276-E8285
DeWitt 3rd, William S; Smith, Anajane; Schoch, Gary et al. (2018) Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity. Elife 7:
Moore, James; Ahmed, Hasan; Jia, Jonathan et al. (2018) What Controls the Acute Viral Infection Following Yellow Fever Vaccination? Bull Math Biol 80:46-63
Moore, James; Ahmed, Hasan; Antia, Rustom (2018) High dimensional random walks can appear low dimensional: Application to influenza H3N2 evolution. J Theor Biol 447:56-64
Olson, Branden J; Matsen 4th, Frederick A (2018) The Bayesian optimist's guide to adaptive immune receptor repertoire analysis. Immunol Rev 284:148-166
Zarnitsyna, Veronika I; Bulusheva, Irina; Handel, Andreas et al. (2018) Intermediate levels of vaccination coverage may minimize seasonal influenza outbreaks. PLoS One 13:e0199674
Youngblood, Ben; Hale, J Scott; Kissick, Haydn T et al. (2017) Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature 552:404-409
Handel, Andreas (2017) Learning infectious disease epidemiology in a modern framework. PLoS Comput Biol 13:e1005642
Pawelek, Kasia A; Dor Jr, Daniel; Salmeron, Cristian et al. (2016) Within-Host Models of High and Low Pathogenic Influenza Virus Infections: The Role of Macrophages. PLoS One 11:e0150568
Lipsitch, Marc; Barclay, Wendy; Raman, Rahul et al. (2016) Viral factors in influenza pandemic risk assessment. Elife 5:

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