Abstract

A dedicated administrative infrastructure will be established to oversee and manage the Infrastructure and Opportunities Fund (IOF). This Core will assume responsibility for managing the IOF, including disbursement and tracking of IOF funds, establishing an administrative structure to manage the IOF, and reporting on the status of IOF projects and expenditures to the NIAID and HIPC Steering Committee. A full time administrator will be appointed to interface with each of the U19 Program Directors and with the HIPC Steering Committee, under the supervision of Dr. Garca-Sastre, co-I in the Dengue Human Immunology Project Consortium (DHIPC), and member of the DHIPC Executive Committee. This individual's responsibility will be to implement the utilization of the IOF under direction of the HIPC Steering Committee.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI118610-03
Application #
9293240
Study Section
Special Emphasis Panel (ZAI1-LGR-I)
Project Start
Project End
Budget Start
2017-06-01
Budget End
2018-05-31
Support Year
3
Fiscal Year
2017
Total Cost
$133,644
Indirect Cost
$54,798

  Institution

Name
Icahn School of Medicine at Mount Sinai
Department
Type
Domestic Higher Education
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Katzelnick, Leah C; Ben-Shachar, Rotem; Mercado, Juan Carlos et al. (2018) Dynamics and determinants of the force of infection of dengue virus from 1994 to 2015 in Managua, Nicaragua. Proc Natl Acad Sci U S A 115:10762-10767
Mishra, Nischay; Caciula, Adrian; Price, Adam et al. (2018) Diagnosis of Zika Virus Infection by Peptide Array and Enzyme-Linked Immunosorbent Assay. MBio 9:
Janssens, Sylvie; Schotsaert, Michael; Manganaro, Lara et al. (2018) FACS-Mediated Isolation of Neuronal Cell Populations From Virus-Infected Human Embryonic Stem Cell-Derived Cerebral Organoid Cultures. Curr Protoc Stem Cell Biol :e65
Thézé, Julien; Li, Tony; du Plessis, Louis et al. (2018) Genomic Epidemiology Reconstructs the Introduction and Spread of Zika Virus in Central America and Mexico. Cell Host Microbe 23:855-864.e7
Patil, Veena S; Madrigal, Ariel; Schmiedel, Benjamin J et al. (2018) Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis. Sci Immunol 3:
Manganaro, Lara; Hong, Patrick; Hernandez, Matthew M et al. (2018) IL-15 regulates susceptibility of CD4+ T cells to HIV infection. Proc Natl Acad Sci U S A 115:E9659-E9667
Andrade, Paulina; Coloma, Josefina; Harris, Eva (2018) ELISPOT-Based ""Multi-Color FluoroSpot"" to Study Type-Specific and Cross-Reactive Responses in Memory B Cells after Dengue and Zika Virus Infections. Methods Mol Biol 1808:151-163
Wang, Daifeng; Liu, Shuang; Warrell, Jonathan et al. (2018) Comprehensive functional genomic resource and integrative model for the human brain. Science 362:
Michlmayr, Daniela; Pak, Theodore R; Rahman, Adeeb H et al. (2018) Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases. Mol Syst Biol 14:e7862
Tsai, Wen-Yang; Youn, Han Ha; Tyson, Jasmine et al. (2018) Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections. Emerg Infect Dis 24:1355-1359

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