Each of the tour proposed research projects associated with this Developmental Center for Research in Osteopathic Manipulative Medicine (DCR-OMM) stands on its own scientific merit and each has an independent team of investigators capable of completing their research plans as proposed. However, in order to optimize the efficiency and value of each project, it is clear that the research teams must effectively communicate across the four R-21 projects. This is especially true for the uniquely osteopathic components of this research that relates to the clinical application of the osteopathic manipulative medicine (OMM). An Osteopathic Core (O-Core) will be established to enhance the research productivity of each individual R-21 project and that of the DCR-OMM as a whole. The O-Core is comprised of all of the osteopathic physicians who are listed as either PI or Co-I on each of the component R-21 projects of this DCR-OMM plus five other osteopathic physicians. The Director of the O-Core will represent the O-Core at the Internal Steering Committee meetings.
The specific aims of the Osteopathic Core include: 1. Guide the DCR-OMM research to maintain focus on mechanisms of actions of OMM that are clinically relevant. 2. Enhance communication and synergy across the entire DCR-OMM and its component R-21 research projects. 3. Link the DCR-OMM to established local and national resources of OMM research expertise. 4. Ensure substantial involvement for OMM clinicians in present and future research planning. Regular communication between osteopathic physicians participating in the O-Core will help enhance the overall osteopathic relevance and synergy of this DCR-OMM. This O-Core is needed to ensure that all research projects maintain maximum focus on evaluating the mechanisms by which OMM has its clinical effects.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AT002023-01A1
Application #
6880838
Study Section
Special Emphasis Panel (ZAT1-DB (14))
Project Start
2004-09-01
Project End
2007-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
1
Fiscal Year
2004
Total Cost
$42,408
Indirect Cost
Name
University of North Texas
Department
Type
DUNS #
110091808
City
Fort Worth
State
TX
Country
United States
Zip Code
76107
Hensel, Kendi L; Pacchia, Christina F; Smith, Michael L (2013) Acute improvement in hemodynamic control after osteopathic manipulative treatment in the third trimester of pregnancy. Complement Ther Med 21:618-26
Cao, Thanh V; Hicks, Michael R; Standley, Paul R (2013) In vitro biomechanical strain regulation of fibroblast wound healing. J Am Osteopath Assoc 113:806-18
Giles, Paul D; Hensel, Kendi L; Pacchia, Christina F et al. (2013) Suboccipital decompression enhances heart rate variability indices of cardiac control in healthy subjects. J Altern Complement Med 19:92-6
Schander, Artur; Downey, H Fred; Hodge, Lisa M (2012) Lymphatic pump manipulation mobilizes inflammatory mediators into lymphatic circulation. Exp Biol Med (Maywood) 237:58-63
Hodge, Lisa M; Downey, H Fred (2011) Lymphatic pump treatment enhances the lymphatic and immune systems. Exp Biol Med (Maywood) 236:1109-15
Meltzer, Kate R; Cao, Thanh V; Schad, Joseph F et al. (2010) In vitro modeling of repetitive motion injury and myofascial release. J Bodyw Mov Ther 14:162-71
Hodge, Lisa M; Bearden, Melissa K; Schander, Artur et al. (2010) Lymphatic pump treatment mobilizes leukocytes from the gut associated lymphoid tissue into lymph. Lymphat Res Biol 8:103-10
Prajapati, Parna; Shah, Pankhil; King, Hollis H et al. (2010) Lymphatic pump treatment increases thoracic duct lymph flow in conscious dogs with edema due to constriction of the inferior vena cava. Lymphat Res Biol 8:149-54
Standley, Paul R; Meltzer, Kate (2008) In vitro modeling of repetitive motion strain and manual medicine treatments: potential roles for pro- and anti-inflammatory cytokines. J Bodyw Mov Ther 12:201-3
Downey, H Fred; Durgam, Preethi; Williams Jr, Arthur G et al. (2008) Lymph flow in the thoracic duct of conscious dogs during lymphatic pump treatment, exercise, and expansion of extracellular fluid volume. Lymphat Res Biol 6:3-13

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