The primary function of the bioanalytical mass spectrometry core is to identify and quantitate individual molecular species from crude extracts from individual laboratory programs. This will involve utilizing established methods such as high resolution FAB MS, low resolution ESI, MSI, and tandem mass spectrometry (neutral loss, precursor ion,, and product ion scans.) Furthermore, new HPLC-MS/MS methods incorporating MRM scans will be developed with regard to automation, high-throughput, and sample screening; metabolism, and quantitation of naturally occurring sphingolipids; as well as digestion, metabolism. and quantitation of sphingoid analogs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19CA087525-02
Application #
6453633
Study Section
Special Emphasis Panel (ZCA1)
Project Start
2001-06-01
Project End
2001-08-31
Budget Start
Budget End
Support Year
2
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Emory University
Department
Type
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
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