The overall intent of the Outreach and Promotion Core is to provide integrated scientific, educational, administrative, and financial support for outreach efforts, training, and pilot projects related to the West Coast Central Comprehensive Metabolomics Resource Core (WC^MRC) mission. The Core will incorporates highly successful aspects of the UC Davis Clinical and Translational Science Center (CTSC) programs including the Research Education, Training, and Career Development Program, the Pilot Translational and Clinical Studies Program, and the Translational Technologies, Methodologies, and Resources Program that have been developed and thoroughly tested during 6 years of NIH funding. Offerings through the CTSC Education Program will be supplemented with new translational metabolomics core courses, seminars, and workshops that will provide crucial exposure of a spectrum of trainees to the metabolomics field. Examples for such workshops offered through this core will be Glycobiology and the Microbiome, Cancer Metabolism, Lipid Metabolism in Cardiovascular Diseases and Metabolic Pathways in Animal Models. Examples for specific metabolomic training courses are Metabolomics Basics, Advanced Metabolomics and Genomics in Metabolic Diseases, to be inclusive for all trainees in the WC^MRC with hands-on training experience opportunities. Importantly, the Core will engage regional and local scientists to participate in pilot and feasibility project programs. These programs aim to spark innovative and collaborative scientific endeavors by supporting and facilitating robust new research paradigms, technologies, and tools, and through partnerships that enhance team science. The basic principles in executing the pilot program include: (1) a requirement for submissions to represent new multidisciplinary teams;(2) the inclusion of trainees and exposure of these trainees to the WC^MRC and CTSC educational offerings;(3) active solicitation of partnerships and leveraging of funds from other UC Davis pilot programs;and (4) linking program announcements to translational workshops.

Public Health Relevance

Studying and understanding metabolism in a comprehensive way is important to fight metabolic diseases, including diabetes, heart attacks, strokes, and cancer. Educating the next generation of scientist who can use modern tools in metabolic analysis lays the foundation for breakthroughs in understanding and treating metabolic diseases.

Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
City
Davis
State
CA
Country
United States
Zip Code
95618
Shahid, Muhammad; Lee, Min Young; Yeon, Austin et al. (2018) Menthol, a unique urinary volatile compound, is associated with chronic inflammation in interstitial cystitis. Sci Rep 8:10859
Hook, Vivian; Lietz, Christopher B; Podvin, Sonia et al. (2018) Diversity of Neuropeptide Cell-Cell Signaling Molecules Generated by Proteolytic Processing Revealed by Neuropeptidomics Mass Spectrometry. J Am Soc Mass Spectrom 29:807-816
Hernandez-Carretero, A; Weber, N; La Frano, M R et al. (2018) Obesity-induced changes in lipid mediators persist after weight loss. Int J Obes (Lond) 42:728-736
Agrawal, Karan; Waller, Justin D; Pedersen, Theresa L et al. (2018) Effects of stimulation technique, anatomical region, and time on human sweat lipid mediator profiles. Prostaglandins Other Lipid Mediat 134:84-92
Jung, Jae Hun; You, Sungyong; Oh, Jae Won et al. (2018) Integrated proteomic and phosphoproteomic analyses of cisplatin-sensitive and resistant bladder cancer cells reveal CDK2 network as a key therapeutic target. Cancer Lett 437:1-12
Barupal, Dinesh Kumar; Fan, Sili; Wancewicz, Benjamin et al. (2018) Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort. Sci Data 5:180263
Fong, Louise Y; Jing, Ruiyan; Smalley, Karl J et al. (2018) Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats. Proc Natl Acad Sci U S A 115:E11091-E11100
Pedersen, Theresa L; Newman, John W (2018) Establishing and Performing Targeted Multi-residue Analysis for Lipid Mediators and Fatty Acids in Small Clinical Plasma Samples. Methods Mol Biol 1730:175-212
Ha, Yun-Sok; Kim, Yeon-Yong; Yu, Na Hee et al. (2018) Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway. Investig Clin Urol 59:263-274
Gao, Bei; Gallagher, Tara; Zhang, Ying et al. (2018) Tracking Polymicrobial Metabolism in Cystic Fibrosis Airways: Pseudomonas aeruginosa Metabolism and Physiology Are Influenced by Rothia mucilaginosa-Derived Metabolites. mSphere 3:

Showing the most recent 10 out of 184 publications