Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The general goal of this project is to exploit the flexibility of RF excitation and RF sensitivity profiles for the development of hybrid imaging sequences and to make these methods available as a resource for enhancing MRI-guided therapy applications, in particular, MRI-based monitoring of thermal therapies.
Our specific aims to achieve this goal are to: (1) Develop hybrid imaging sequences for image-guided therapy combining non-Fourier and RF encoding with standard Fourier-encoded MRI methods. (2) Develop motion-robust, single-shot spin-echo line-scan and slab-scan sequences with multiple contrasts for image-guided therapy, (3) Develop a variety of parallel imaging implementations tailored to the needs of image-guided therapy.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Cooperative Agreements (U41)
Project #
5U41RR019703-05
Application #
7960864
Study Section
Special Emphasis Panel (ZRG1-SBIB-L (40))
Project Start
2009-08-01
Project End
2010-07-31
Budget Start
2009-08-01
Budget End
2010-07-31
Support Year
5
Fiscal Year
2009
Total Cost
$1,147,359
Indirect Cost

  Institution

Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Schmidt, Ehud J; Halperin, Henry R (2018) MRI use for atrial tissue characterization in arrhythmias and for EP procedure guidance. Int J Cardiovasc Imaging 34:81-95
George, E; Liacouras, P; Lee, T C et al. (2017) 3D-Printed Patient-Specific Models for CT- and MRI-Guided Procedure Planning. AJNR Am J Neuroradiol 38:E46-E47
Mitsouras, Dimitris; Lee, Thomas C; Liacouras, Peter et al. (2017) Three-dimensional printing of MRI-visible phantoms and MR image-guided therapy simulation. Magn Reson Med 77:613-622
Guenette, Jeffrey P; Himes, Nathan; Giannopoulos, Andreas A et al. (2016) Computer-Based Vertebral Tumor Cryoablation Planning and Procedure Simulation Involving Two Cases Using MRI-Visible 3D Printing and Advanced Visualization. AJR Am J Roentgenol 207:1128-1131
Mitsouras, Dimitris; Mulkern, Robert V; Maier, Stephan E (2016) Multicomponent T2 relaxation studies of the avian egg. Magn Reson Med 75:2156-64
Li, Mao; Miller, Karol; Joldes, Grand Roman et al. (2016) Biomechanical model for computing deformations for whole-body image registration: A meshless approach. Int J Numer Method Biomed Eng 32:
Schmidt, Ehud J; Watkins, Ronald D; Zviman, Menekhem M et al. (2016) A Magnetic Resonance Imaging-Conditional External Cardiac Defibrillator for Resuscitation Within the Magnetic Resonance Imaging Scanner Bore. Circ Cardiovasc Imaging 9:
Tempany, Clare M C; Jayender, Jagadeesan; Kapur, Tina et al. (2015) Multimodal imaging for improved diagnosis and treatment of cancers. Cancer 121:817-27
Abd-El-Barr, Muhammad M; Santos, Seth M; Aglio, Linda S et al. (2015) ""Extraoperative"" MRI (eoMRI) for Brain Tumor Surgery: Initial Results at a Single Institution. World Neurosurg 83:921-8
Li, Mao; Miller, Karol; Joldes, Grand Roman et al. (2015) Patient-specific biomechanical model as whole-body CT image registration tool. Med Image Anal 22:22-34

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