Project Start
2004-09-01
Project End
2005-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
5
Fiscal Year
2004
Total Cost
$225,955
Indirect Cost
Name
Oregon Health and Science University
Department
Type
Other Domestic Higher Education
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Jaworski, J Pablo; Kobie, James; Brower, Zachary et al. (2013) Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques. J Virol 87:10447-59
Hansen, Scott G; Powers, Colin J; Richards, Rebecca et al. (2010) Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus. Science 328:102-6
Okoye, Afam; Park, Haesun; Rohankhedkar, Mukta et al. (2009) Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis. J Exp Med 206:1575-88
Murray, Shannon M; Picker, Louis J; Axthelm, Michael K et al. (2008) Replication in a superficial epithelial cell niche explains the lack of pathogenicity of primate foamy virus infections. J Virol 82:5981-5
Price, David A; Bitmansour, Arlene D; Edgar, John B et al. (2008) Induction and evolution of cytomegalovirus-specific CD4+ T cell clonotypes in rhesus macaques. J Immunol 180:269-80
Okoye, Afam; Meier-Schellersheim, Martin; Brenchley, Jason M et al. (2007) Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection. J Exp Med 204:2171-85
Picker, Louis J; Reed-Inderbitzin, Edward F; Hagen, Shoko I et al. (2006) IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates. J Clin Invest 116:1514-24
Margolin, David H; Saunders, Erika H; Bronfin, Benjamin et al. (2006) Germinal center function in the spleen during simian HIV infection in rhesus monkeys. J Immunol 177:1108-19
Murray, S M; Picker, L J; Axthelm, M K et al. (2006) Expanded tissue targets for foamy virus replication with simian immunodeficiency virus-induced immunosuppression. J Virol 80:663-70
Picker, Louis J; Hagen, Shoko I; Lum, Richard et al. (2004) Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection. J Exp Med 200:1299-314

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