Research Education Core Key Personnel: Debra L. Laskin, Ph.D., Core Lead Lauren M. Aleksunes, Pharm.D., Ph.D., Co-Lead Diane E. Heck, Ph.D., Collaborator Joshua P. Gray, Ph.D., Collaborator Core Summary/Abstract The Rutgers CounterACT Center has established a comprehensive, multidisciplinary Research Education Core directed at undergraduates, medical and graduate students, postdoctoral trainees and new and established investigators. The primary functions of the Research Education Core are to 1) increase the engagement of researchers in chemical threat-related research, 2) provide innovative educational activities for technicians, medical and graduate students, postdoctoral trainees, and established investigators, 3) enhance literacy and awareness of participants regarding the toxicology of chemical threats, and 4) disseminate teaching materials and assessment metrics. These functions are achieved through seminars, symposia, coursework, distance education programs, thesis projects, research fellowships, and directed laboratory modules. The leadership team of the Education Core is comprised of 4 tenured faculty members spanning 3 institutions who have expertise in mentoring, training program management, toxicology education, distance learning, and development of curricula. The Education Core draws upon the resources, infrastructure, and expertise of faculty appointed across the four academic institutions and draws strength from additional institutional grants including T32, P30, and R25 grants from NIH/NIEHS. In the renewal application, we propose to enhance training opportunities for our current trainee pool as well as expand the reach of our initiatives to high school students and the general public using a combination of live workshops, industry internships, and community engagement activities. Emphasis will also be placed on standardized assessment of activities, dissemination of program outcomes, and tracking of participants in the Education Core. The Education Core has made tremendous achievements in the prior funding period that will be augmented and expanded over the next 5 years.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54AR055073-15
Application #
9982798
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
15
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Rbhs-School of Public Health
Department
Type
DUNS #
078795880
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Moretti, Alysha; Li, Qi; Chmielowski, Rebecca et al. (2018) Nanotherapeutics Containing Lithocholic Acid-Based Amphiphilic Scorpion-Like Macromolecules Reduce In Vitro Inflammation in Macrophages: Implications for Atherosclerosis. Nanomaterials (Basel) 8:
Szilagyi, John T; Fussell, Karma C; Wang, Yun et al. (2018) Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase. Toxicol Appl Pharmacol 359:102-107
Joseph, Laurie B; Composto, Gabriella M; Perez, Roberto M et al. (2018) Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug. Toxicol Lett 293:77-81
Chang, Yoke-Chen; Gordon, Marion K; Gerecke, Donald R (2018) Expression of Laminin 332 in Vesicant Skin Injury and Wound Repair. Clin Dermatol (Wilmington) 2:
Yang, Shaojun; Jan, Yi-Hua; Mishin, Vladimir et al. (2017) Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells. Chem Res Toxicol 30:1406-1418
Venosa, Alessandro; Gow, James G; Hall, LeRoy et al. (2017) Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacetylase Inhibitor. Toxicol Sci 157:222-234
Francis, Mary; Sun, Richard; Cervelli, Jessica A et al. (2017) Editor's Highlight: Role of Spleen-Derived Macrophages in Ozone-Induced Lung Inflammation and Injury. Toxicol Sci 155:182-195
Chmielowski, Rebecca A; Abdelhamid, Dalia S; Faig, Jonathan J et al. (2017) Athero-inflammatory nanotherapeutics: Ferulic acid-based poly(anhydride-ester) nanoparticles attenuate foam cell formation by regulating macrophage lipogenesis and reactive oxygen species generation. Acta Biomater 57:85-94
Francis, Mary; Groves, Angela M; Sun, Richard et al. (2017) Editor's Highlight: CCR2 Regulates Inflammatory Cell Accumulation in the Lung and Tissue Injury following Ozone Exposure. Toxicol Sci 155:474-484
Malaviya, Rama; Laskin, Jeffrey D; Laskin, Debra L (2017) Anti-TNF? therapy in inflammatory lung diseases. Pharmacol Ther 180:90-98

Showing the most recent 10 out of 145 publications