PLANNING AND EVALUATION COREThis section describes the Planning and Evaluation Core. The overall goal of the Planning and EvaluationCore is to assess the progress of the collaboration. Toward that end, the Planning and Evaluation Core willreview the various components of the partnership to ensure that the goals and objectives of the collaborationare met. The committees established in this Core will meet regularly to review and establish short- and longtermgoals, progress of the projects, and will review new pilot projects for the development Core.Internal ProcessesThe Internal Advisory Committee (IAC) is comprised of scientists at the FHCRC and NMSU. Each individualwas selected based on his/her knowledge and expertise of areas related to this application. The IACmembership is briefly described below.New Mexico MembersCarl Kendall. Dr. Kendall is the new holder of the Stan Fulton Endowed Chair in Health Disparities and directorfor the Southwest Center for Health Disparities Research. He also serves as Associate Dean for Research forthe College of Health and Human Services at NMSU. Kendall is new to NMSU after a career at the TulaneUniversity School of Public Health and Tropical Medicine in Louisiana, and The Johns Hopkins BloombergSchool of Pubic Health. Dr. Kendall received the distinguished research faculty award from Tulane for 2002,2003, 2004 and 2005. He has collaborated with colleagues at the Tulane Cancer Center and the LouisianaCancer Consortium where he mentored junior faculty to develop proposals to enhance breast cancer screeningamong African-American populations. He has collaborated with colleagues in more than 40 countries toaddress global problems of maternal and childhood illnesses, vector-borne diseases, and HIV/AIDS. CurrentlyKendall manages projects in eight countries with full-time staff in four of those countries. Dr. Kendall is fluentin Spanish and has taught university graduate courses in Spain and Guatemala.Vimal Chaitanva. Before becoming the NMSU Vice President for Research Graduate Studies and InternationalPrograms in July 2006, Dr. Chaitanya was the director of the Advanced Materials Processing and AnalysisCenter (AMPAC) at the University of Central Florida (UCF). He was also the director of UCF's MaterialsScience and Engineering program and its Materials Characterization Facility. Dr. Chaitanya received theUniversity of Central Florida's Research Achievement Award in 2002 and the UCF Leadership Award in 1999.He is a five-time winner of his academic department's Researcher of the Year award. He has a Ph.D. inmaterials science and engineering from The Johns Hopkins University in Baltimore, a master's degree inbioengineering from Clemson University in South Carolina, and a bachelor's degree in mechanical engineeringfrom M.S. University of Baroda, India.Fred Hutchinson Cancer Research Center MembersHarmit S. Malik. Dr. Malik is an Assistant Member at the FHCRC and an Affiliate Assistant Professor ofGenome Sciences at the University of Washington. Dr. Malik's lab is interested in evolutionary studies ofgenetic conflict to gain insights into their mechanisms and consequences. Genomes are a tenuousconglomerate of different genetics entities, each trying to maximize their own evolutionary success, often atgreat cost to their genomic neighbors. This can create problems for the host organism. To gain insights intothese mechanisms, Dr. Malik's lab studies centromeres, mobile genetic elements, and rapidly evolving proteinsin Drosophila. Dr. Malik will provide great expertise in biology and the drosophila studies.Julian Simon. Dr. Simon is an Associate Member at the FHCRC and an Affiliate Associate Professor in theMolecular and Cellular Biology Program at the University of Washington.
The aim of his lab is to identify newanticancer drugs. This is done through using the genetic context of the cancer cell as the drug target. Thesecond broad strategy is to use chemical genetics to find better anticancer drugs. Other projects in the labinclude the study of genetic interactions of mismatch repair mutants with ribonucleotide reductase as a strategyfor the identification of drugs for the treatment of tumors with mismatch repair defects. Dr. Simon was involvedin the U56 and has excellent understanding of how the collaboration operates.Ad Hoc Members ' 'Whenever there is a call for new proposals within the U54 collaboration, a 'study section' will be convened toreview and critique the proposals. We followed this format during the U56 award and found this to be aneffective way to match proposals with expertise in the areas covered by the proposal. Members from bothinstitutions will be identified and recruited by the IAC to review proposals (see below). These reviewers willform a study section to discuss and rank the proposals received and to make recommendations forimprovements.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54CA132381-01
Application #
7419419
Study Section
Special Emphasis Panel (ZCA1-SRRB-Y (O1))
Project Start
2007-09-30
Project End
2012-08-31
Budget Start
2007-09-30
Budget End
2008-08-31
Support Year
1
Fiscal Year
2007
Total Cost
$58,158
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
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