3.g Human Imaging Unit (HID) in the Center for Clinical Imaging Research (CCIR)The Human Imaging Unit (HIU) is a core facility established under the NIH-funded Clinical Sciences andTranslational Award (CSTA) program that provides advanced instrumentation for human image acquisition,archiving, processing, and analysis. The HIU is part of the Center for Clinical Imaging Research (CCIR) atMallinckrodt Institute of Radiology at Washington University School of Medicine, which is internationallyrenowned for its imaging research, training and development of new technology. Major goals of the HIU are tosupport the development of novel methods and approaches to address clinical and translational research byproviding: 1) access to the instrumentation & resources needed to conduct advanced research imagingstudies; 2) the expertise needed to design and conduct appropriate imaging protocols and to createnew/innovative human imaging tools, workflow processes, and biomedical informatics systems; 3) the supportneeded to analyze imaging data; and, 4) educational programs to increase networking and available training inimaging techniques. The HIU will serve as the primary coordinating hub for the validation componentsdescribed in this U54 grant application.Since the CCIR is located directly above the main entrance for the Barnes-Jewish Hospital, easy access isavailable for inpatients, outpatients, control subjects and healthy volunteers. As part of the CCIR, the HIU hasaccess to a full range imaging services and state-of-the-art hardware, including six dedicated researchscanners, namely, (1) 3T MRI MAGNETOM (Trio, a Tim System), (2) PET/CT Biograph 40 Tomograph, (3) CTSOMATOM Definition, (4) 1.5T MRI MAGNETOM Avanto, (5) PET ECAT HR+ 962, and (6) UltrasoundACUSON Antares.More than 2000 square feet of the CCIR is devoted to staff work areas such as image workstations for dataprocessing, a nursing station, research coordinator workstations, offices and conference rooms. Patient areasinclude holding rooms, dressing rooms with lockers, and consult rooms for exams and consenting. The HIU viathe CCIR has access to these resources and can provide extensive imaging-related support.
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