Abstract

Public Health Relevance

MC-START is structured around a set of interconnected research projects that are looking at tumor behavior from a variety of perspectives. As a consequence, the results are heterogeneous sets of data that need to be combined into integrated multi-scale models that form the unique perspective and approach proposed by MC-START. This project provides this essential infrastructure required to create the integrated model,

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54CA143907-01
Application #
7802575
Study Section
Special Emphasis Panel (ZCA1-SRLB-9 (O1))
Project Start
2009-09-01
Project End
2014-07-31
Budget Start
2009-09-28
Budget End
2010-07-31
Support Year
1
Fiscal Year
2009
Total Cost
$129,923
Indirect Cost

  Institution

Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089

  Publications

Ng, Chin F; Frieboes, Hermann B (2018) Simulation of Multispecies Desmoplastic Cancer Growth via a Fully Adaptive Non-linear Full Multigrid Algorithm. Front Physiol 9:821
Tipton, Laura; Müller, Christian L; Kurtz, Zachary D et al. (2018) Fungi stabilize connectivity in the lung and skin microbial ecosystems. Microbiome 6:12
Lee, Jung-Rok; Appelmann, Iris; Miething, Cornelius et al. (2018) Longitudinal Multiplexed Measurement of Quantitative Proteomic Signatures in Mouse Lymphoma Models Using Magneto-Nanosensors. Theranostics 8:1389-1398
Lee, Jung-Rok; Chan, Carmel T; Ruderman, Daniel et al. (2017) Longitudinal Monitoring of Antibody Responses against Tumor Cells Using Magneto-nanosensors with a Nanoliter of Blood. Nano Lett 17:6644-6652
Yan, Huaming; Romero-Lopez, Monica; Frieboes, Hermann B et al. (2017) Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression Without Increasing Invasiveness. IEEE Trans Biomed Eng 64:538-548
Yan, Huaming; Romero-López, Mónica; Benitez, Lesly I et al. (2017) 3D Mathematical Modeling of Glioblastoma Suggests That Transdifferentiated Vascular Endothelial Cells Mediate Resistance to Current Standard-of-Care Therapy. Cancer Res 77:4171-4184
Tennill, Thomas A; Gross, Mitchell E; Frieboes, Hermann B (2017) Automated analysis of co-localized protein expression in histologic sections of prostate cancer. PLoS One 12:e0178362
Ware, Matthew J; Curtis, Louis T; Wu, Min et al. (2017) Pancreatic adenocarcinoma response to chemotherapy enhanced with non-invasive radio frequency evaluated via an integrated experimental/computational approach. Sci Rep 7:3437
Ng, Chin F; Frieboes, Hermann B (2017) Model of vascular desmoplastic multispecies tumor growth. J Theor Biol 430:245-282
Garvey, Colleen M; Gerhart, Torin A; Mumenthaler, Shannon M (2017) Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques. J Vis Exp :

Showing the most recent 10 out of 128 publications