The Administrative Core (AC) will function to manage the CAC and help administer and support the PSOCMC- SMART. The will help coordinate the CAC twice monthly meetings. The CAC, together with the program manager, will assure that project and core plans progress, postdoctoral fellows are shared, training and outreach efforts are implemented, pilot projects are encouraged and funded, and the 'business'of the program is accomplished. A key element of the AC will be a full time program manager who will work closely with Drs. Hillis as well the other members of the Center Advisory Committee to help execute all recommendations of the CAC, NCI Project Scientist and the PSC. The AC will assure that all meeting generated notes/reports to the CAC and PSC are prepared and disseminated. Additionally, as both integrative education and community outreach are such significant portions of the PSOC-MC-START program, the AC will be managing the PSOC-MC-SMART website and the implementation of the PSOC-MCSTART member ectures/seminars in both the i) newly planned series, and the ii) leveraged series at our collaborating institutions, and professional association meetings, to educate about physical sciences and oncology.

Public Health Relevance

Clinical tools to accurately describe, evaluate and predict an individual's response to cancer therapy are a field-wide priority. Through our virtual cancer, we anticipate it will become possible to take a small number of measurements from a patient, input those measurements as calibrants to our virtual cancer and then simulate the growth and response to therapy of the patient.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA143907-02
Application #
7942786
Study Section
Special Emphasis Panel (ZCA1-SRLB-9 (O1))
Program Officer
Lee, Jerry S
Project Start
2009-09-28
Project End
2014-07-31
Budget Start
2010-08-01
Budget End
2011-07-31
Support Year
2
Fiscal Year
2010
Total Cost
$3,144,049
Indirect Cost
Name
University of Southern California
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Ng, Chin F; Frieboes, Hermann B (2018) Simulation of Multispecies Desmoplastic Cancer Growth via a Fully Adaptive Non-linear Full Multigrid Algorithm. Front Physiol 9:821
Tipton, Laura; Müller, Christian L; Kurtz, Zachary D et al. (2018) Fungi stabilize connectivity in the lung and skin microbial ecosystems. Microbiome 6:12
Lee, Jung-Rok; Appelmann, Iris; Miething, Cornelius et al. (2018) Longitudinal Multiplexed Measurement of Quantitative Proteomic Signatures in Mouse Lymphoma Models Using Magneto-Nanosensors. Theranostics 8:1389-1398
Ng, Chin F; Frieboes, Hermann B (2017) Model of vascular desmoplastic multispecies tumor growth. J Theor Biol 430:245-282
Garvey, Colleen M; Gerhart, Torin A; Mumenthaler, Shannon M (2017) Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques. J Vis Exp :
Lee, Jung-Rok; Chan, Carmel T; Ruderman, Daniel et al. (2017) Longitudinal Monitoring of Antibody Responses against Tumor Cells Using Magneto-nanosensors with a Nanoliter of Blood. Nano Lett 17:6644-6652
Yan, Huaming; Romero-Lopez, Monica; Frieboes, Hermann B et al. (2017) Multiscale Modeling of Glioblastoma Suggests that the Partial Disruption of Vessel/Cancer Stem Cell Crosstalk Can Promote Tumor Regression Without Increasing Invasiveness. IEEE Trans Biomed Eng 64:538-548
Yan, Huaming; Romero-López, Mónica; Benitez, Lesly I et al. (2017) 3D Mathematical Modeling of Glioblastoma Suggests That Transdifferentiated Vascular Endothelial Cells Mediate Resistance to Current Standard-of-Care Therapy. Cancer Res 77:4171-4184
Tennill, Thomas A; Gross, Mitchell E; Frieboes, Hermann B (2017) Automated analysis of co-localized protein expression in histologic sections of prostate cancer. PLoS One 12:e0178362
Ware, Matthew J; Curtis, Louis T; Wu, Min et al. (2017) Pancreatic adenocarcinoma response to chemotherapy enhanced with non-invasive radio frequency evaluated via an integrated experimental/computational approach. Sci Rep 7:3437

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