Abstract

In this application, we propose to intensify the role of our existing MVTCP shared resource cores: Clinical Trials Core (CTC), Bioinfomatics and Biostatistics Core (BBC), and Translational Pathology Core (TPC). These cores have been instrumental in the success of our Cancer Partnership in the previous funding cycles and will continue to facilitate and accelerate the success of full research projects (3), pilot project (1), as well as the Education and Cancer Outreach cores. In this renewal application, specific aims for the Cores are to: 1. Promote and support access of minority and underserved patients onto clinical trials that are usually not available at community public hospitals (Clinical Trials Core); 2. Provide professional expertise in biostatistics and bioinformatics for all cancer-related research in the MVTCP (Bioinfomatics and Biostatistics Core); and 3. Facilitate studies of MVTCP investigators that involve tissue analysis by collecting and banking human tissues from majority and minority populations and providing state of the art technology for analysis of these tissues along with instruction to students and faculty on the latest technologies available (Translational Pathology Core).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54CA163069-06
Application #
9211642
Study Section
Special Emphasis Panel (ZCA1-SRB-X (A1))
Project Start
Project End
Budget Start
2016-09-01
Budget End
2017-08-31
Support Year
6
Fiscal Year
2016
Total Cost
$407,121
Indirect Cost
$127,313

  Institution

Name
Meharry Medical College
Department
Type
DUNS #
041438185
City
Nashville
State
TN
Country
United States
Zip Code
37208

  Publications

Xie, Yingqiu; Fan, Haiyan; Lu, Wenfu et al. (2018) Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer. Oncogene :
Odoh, C; Sanderson, M; Williams, E A et al. (2018) Operationalizing outcome measures of human papillomavirus vaccination among adolescents. Public Health 159:129-132
Ochieng, Josiah; Nangami, Gladys; Sakwe, Amos et al. (2018) Extracellular histones are the ligands for the uptake of exosomes and hydroxyapatite-nanoparticles by tumor cells via syndecan-4. FEBS Lett 592:3274-3285
Abney, Kristopher K; Ramos-Hunter, Susan J; Romaine, Ian M et al. (2018) Selective Activation of N,N'-Diacyl Rhodamine Pro-fluorophores Paired with Releasing Enzyme, Porcine Liver Esterase (PLE). Chemistry 24:8985-8988
Umeukeje, Ebele M; Wild, Marcus G; Maripuri, Saugar et al. (2018) Black Americans' Perspectives of Barriers and Facilitators of Community Screening for Kidney Disease. Clin J Am Soc Nephrol 13:551-559
Vercruysse, Koen; Clark, Astiney; Alatas, Noor et al. (2018) Polysaccharide-mediated synthesis of melanins from serotonin and other 5-hydroxy indoles. Future Sci OA 4:FSO280
Hull, P C; Buchowski, M; Canedo, J R et al. (2018) Childhood obesity prevention cluster randomized trial for Hispanic families: outcomes of the healthy families study. Pediatr Obes 13:686-696
Sanderson, Maureen; Aldrich, Melinda C; Levine, Robert S et al. (2018) Neighbourhood deprivation and lung cancer risk: a nested case-control study in the USA. BMJ Open 8:e021059
Ochieng, Josiah; Nangami, Gladys; Sakwe, Amos et al. (2018) Impact of Fetuin-A (AHSG) on Tumor Progression and Type 2 Diabetes. Int J Mol Sci 19:
Tantawy, Mohammed N; Charles Manning, H; Peterson, Todd E et al. (2018) Translocator Protein PET Imaging in a Preclinical Prostate Cancer Model. Mol Imaging Biol 20:200-204

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