The administration of the MIT/DFCI CSBC will be administratively based at MIT's Koch Institute of Integrative Cancer Research, an NCI-designated Cancer Center that was established in 1974. This will allow us to leverage an existing, well-organized administrative infrastructure. A part-time Senior Program Administrator will work with the PI/PD on the coordination and administration of the CSBC. The Administrator will have joint reporting to both the PI/PD and to the Assistant Director for Administration at the Koch Institute (KI) to ensure integration with the KI's administrative support services. The resulting structure, for the purposes of this grant, is referred to as the Administrative Unit. The Administrative Unit (AU) will consist of Dr. Scott Manalis, co-Principal Investigator (contact), Ms. Cynthia Quense, the Assistant Director of Administration of the Koch Institute (KI), and Ms. Lori Spindler, Senior Program Administrator. The AU will operate under systems and procedures that exist at the KI and MIT and will manage the day-to-day operations of the CSBC. The overall scientific and technical direction of the CSBC will be provided by the PI/PD in close collaboration with 1) the external advisory members, 2) the lead PI's (Project Leaders), and, 3) Collaborators/Consultants. In addition, Dr. Tyler Jacks, as Director of the Koch Institute for Integrative Cancer Research at MIT will assist in the administrative and scientific oversight of the Center. The overall mission of the Administrative Unit is to provide oversight and coordination on administrative and fiscal aspects of the MIT/DFCI CSBC.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54CA217377-01
Application #
9350739
Study Section
Special Emphasis Panel (ZCA1-RTRB-R (J2))
Project Start
2017-06-07
Project End
2022-04-30
Budget Start
2017-05-11
Budget End
2018-06-30
Support Year
1
Fiscal Year
2017
Total Cost
$181,253
Indirect Cost
$64,089
Name
Massachusetts Institute of Technology
Department
Type
Domestic Higher Education
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02142
Luskin, Marlise R; Murakami, Mark A; Manalis, Scott R et al. (2018) Targeting minimal residual disease: a path to cure? Nat Rev Cancer 18:255-263
Ordovas-Montanes, Jose; Dwyer, Daniel F; Nyquist, Sarah K et al. (2018) Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature 560:649-654
Mead, Benjamin E; Ordovas-Montanes, Jose; Braun, Alexandra P et al. (2018) Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. BMC Biol 16:62
Kimmerling, Robert J; Prakadan, Sanjay M; Gupta, Alejandro J et al. (2018) Linking single-cell measurements of mass, growth rate, and gene expression. Genome Biol 19:207
Cetin, Arif E; Stevens, Mark M; Calistri, Nicholas L et al. (2017) Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation. Nat Commun 8:1613
Shalek, Alex K; Benson, Mikael (2017) Single-cell analyses to tailor treatments. Sci Transl Med 9: