The goal of the """"""""Center for Developing and Testing of Point of Care Tests (POCT) for STDs"""""""" is to support the? development of these tests and work with other Centers to pilot this technology and assure that it is made? available to clinicians and other end users. This goal is compatible with the stated goal of the National? Institutes of Health (NIH), National Institute of Biomedical Imaging and Bioengineering (NIBIB) and positions? the Center to further the agency's mandate. To support the Center's goal, the goal of Core 3 is to? successfully poll clinicians and home users regarding their POCT requisites and to report their requirements? for a POCT to the bench scientists developing such tests.
The specific aims for this Core include:? conducting focus groups for clinicians and other potential """"""""end users""""""""; developing and distributing a needs? assessment; collecting and analyzing the data from the assessment; and disseminating the findings to the? scientific community and survey participants. Developing POCTs that are affordable, sensitive, specific, user? friendly, rapid, robust, equipment-free, deliverable non-invasive assays is essential to support clinical care? 'ancJ;djse'ase prevention. Such tests will offer both providers and home users the opportunity to perform tests? andrgetimmediate: results...At the practice setting or bedside, the results of these assays will assure the? patierit'receives treatment and counseling at that visit, thus, intervening on the disease progression and? ongoing transmission. The test taken at home will alert the patient to the need for treatment, empowering """"""""^? her/him,,tp take a more active role in her/his health care. Both aspects of extending the venue in which tests? can be. performed support the assurance and assessment functions of public health and the associated? directives to prevent disease, limit complications and educate. Sexually transmitted infections (STIs) and? their consequences cost the health care system billions of dollars each year, and every dollar spent on early? intervention has been estimated to save the system twelve dollars in costs for long term care. Incorporating? POCTs into STI prevention and intervention would be essential in developing more rapid response to? outbreaks and epidemics. The role of Core 3 clearly demonstrates the public health functions of assessment? and communication and furthers overall public health awareness.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54EB007958-02
Application #
7637770
Study Section
Special Emphasis Panel (ZEB1)
Project Start
Project End
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
2
Fiscal Year
2008
Total Cost
$78,114
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
(2018) Let's Take A ""Selfie"": Self-Collected Samples for STIs. Sex Transm Dis :
Dize, Laura; Martin, Diana; Gwyn, Sarah et al. (2018) Comparison of three serological assays to measure antibody response to Chlamydia antigen Pgp3 in adolescent and young adults with pelvic inflammatory disease. Int J STD AIDS 29:1324-1329
Horst, Audrey L; Rosenbohm, Justin M; Kolluri, Nikunja et al. (2018) A paperfluidic platform to detect Neisseria gonorrhoeae in clinical samples. Biomed Microdevices 20:35
Dize, Laura; Silver, Barbara; Gaydos, Charlotte (2018) Comparison of the Cepheid GeneXpert CT/NG assay to the Hologic Aptima Combo2 assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in self-collected rectal swabs. Diagn Microbiol Infect Dis 90:83-84
Trent, Maria; Coleman, Jenell S; Hardick, Justin et al. (2018) Clinical and sexual risk correlates of Mycoplasma genitalium in urban pregnant and non-pregnant young women: cross-sectional outcomes using the baseline data from the Women's BioHealth Study. Sex Transm Infect 94:411-413
Crowell, Trevor A; Hardick, Justin; Lombardi, Kara et al. (2018) Asymptomatic lymphogranuloma venereum among Nigerian men who have sex with men. Sex Transm Infect 94:578-581
Pittman, Ellen; Purcell, Hillary; Dize, Laura et al. (2018) Acceptability and feasibility of self-sampling for the screening of sexually transmitted infections in cabana privacy shelters. Int J STD AIDS 29:461-465
Gaydos, Charlotte A (2018) Let's Take A ""Selfie"": Self-Collected Samples for Sexually Transmitted Infections. Sex Transm Dis 45:278-279
Ronda, Jocelyn; Gaydos, Charlotte A; Perin, Jamie et al. (2018) Does the Sex Risk Quiz Predict Mycoplasma genitalium Infection in Urban Adolescents and Young Adult Women? Sex Transm Dis 45:728-734
Melendez, Johan H; Hardick, Justin; Barnes, Mathilda et al. (2018) Molecular Characterization of Markers Associated With Antimicrobial Resistance in Neisseria gonorrhoeae Identified From Residual Clinical Samples. Sex Transm Dis 45:312-315

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