Abstract

In the proposed research we will validate the performance of the OTEG devise on human blood samples. Discarded and de-identified excess human blood samples will be obtained from the MGH coagulation laboratory and from Biological Specialty Corp. (PA, USA). All specimens will be de-identified. Prior to the start of this study, an exempt human subjects protocol will be submitted for approval by the Partners IRB. Research that meets the criteria for Exemption 4 is not considered """"""""clinical research"""""""" as defined by NIH. Therefore, the NIH policies for inclusion of women, minorities and children in clinical research, and targeted/planned enrollment tables, do not apply to research projects covered by Exemption 4.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54EB015408-01
Application #
8467239
Study Section
Special Emphasis Panel (ZEB1-OSR-D (M2))
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
1
Fiscal Year
2012
Total Cost
$175,180
Indirect Cost
$72,661

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Liang, Li-Guo; Kong, Meng-Qi; Zhou, Sherry et al. (2017) An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer. Sci Rep 7:46224
Liang, Li-Guo; Sheng, Ye-Feng; Zhou, Sherry et al. (2017) An Integrated Double-Filtration Microfluidic Device for Detection of Extracellular Vesicles from Urine for Bladder Cancer Diagnosis. Methods Mol Biol 1660:355-364
Batsis, John A; Pletcher, Sarah N; Stahl, James E (2017) Telemedicine and primary care obesity management in rural areas - innovative approach for older adults? BMC Geriatr 17:6
Sher, Mazhar; Zhuang, Rachel; Demirci, Utkan et al. (2017) Paper-based analytical devices for clinical diagnosis: recent advances in the fabrication techniques and sensing mechanisms. Expert Rev Mol Diagn 17:351-366
Sauer-Budge, Alexis F; Brookfield, Samuel J; Janzen, Ronald et al. (2017) A novel device for collecting and dispensing fingerstick blood for point of care testing. PLoS One 12:e0183625
Wang, ShuQi; Lifson, Mark A; Inci, Fatih et al. (2016) Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings. Expert Rev Mol Diagn 16:449-59
Wang, Chien-Chung; Hennek, Jonathan W; Ainla, Alar et al. (2016) A Paper-Based ""Pop-up"" Electrochemical Device for Analysis of Beta-Hydroxybutyrate. Anal Chem 88:6326-33
El Assal, Rami; Gurkan, Umut A; Chen, Pu et al. (2016) 3-D Microwell Array System for Culturing Virus Infected Tumor Cells. Sci Rep 6:39144
Hassan, Umer; Watkins, Nicholas N; Reddy Jr, Bobby et al. (2016) Microfluidic differential immunocapture biochip for specific leukocyte counting. Nat Protoc 11:714-26
Asghar, Waseem; Yuksekkaya, Mehmet; Shafiee, Hadi et al. (2016) Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications. Sci Rep 6:21163

Showing the most recent 10 out of 45 publications