The Administrative Core (directed by Sadis Matalon, PhD) will provide the proper framework that will support, encourage and focus the research efforts of the three projects and of the Exposure Core Facility. This will ensure that all investigators work together as a group, the research efforts remain focused and well integrated and the individual projects generate high quality research to complete their milestones in a timely fashion. Dr. Matalon will also ensure that Dr. Sven Jordt, in spite of the geographical separation, remains well integrated with the rest of the members. In addition the Administrative Core will be responsible for the establishment and maintenance of a Center Website, as specified by the CounterAct Network regulations. Finally, the Director will be in constant touch with NIH personnel and will update the investigators and co-investigators on recent developments.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54ES017218-03
Application #
8107628
Study Section
Special Emphasis Panel (ZNS1)
Project Start
2010-06-29
Project End
2011-05-31
Budget Start
2010-06-29
Budget End
2011-05-31
Support Year
3
Fiscal Year
2010
Total Cost
$114,523
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Song, Weifeng; Yu, Zhihong; Doran, Stephen F et al. (2015) Respiratory syncytial virus infection increases chlorine-induced airway hyperresponsiveness. Am J Physiol Lung Cell Mol Physiol 309:L205-10
Balakrishna, Shrilatha; Song, Weifeng; Achanta, Satyanarayana et al. (2014) TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 307:L158-72
Gessner, Melissa A; Doran, Stephen F; Yu, Zhihong et al. (2013) Chlorine gas exposure increases susceptibility to invasive lung fungal infection. Am J Physiol Lung Cell Mol Physiol 304:L765-73
Li, Changzhao; Weng, Zhiping; Doran, Stephen F et al. (2013) Chlorine induces the unfolded protein response in murine lungs and skin. Am J Respir Cell Mol Biol 49:197-203
Ambalavanan, Namasivayam; Stanishevsky, Andrei; Bulger, Arlene et al. (2013) Titanium oxide nanoparticle instillation induces inflammation and inhibits lung development in mice. Am J Physiol Lung Cell Mol Physiol 304:L152-61
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Bracher, Andreas; Doran, Stephen F; Squadrito, Giuseppe L et al. (2012) Targeted aerosolized delivery of ascorbate in the lungs of chlorine-exposed rats. J Aerosol Med Pulm Drug Deliv 25:333-41
Fanucchi, Michelle V; Bracher, Andreas; Doran, Stephen F et al. (2012) Post-exposure antioxidant treatment in rats decreases airway hyperplasia and hyperreactivity due to chlorine inhalation. Am J Respir Cell Mol Biol 46:599-606
Samal, Andrey A; Honavar, Jaideep; Brandon, Angela et al. (2012) Administration of nitrite after chlorine gas exposure prevents lung injury: effect of administration modality. Free Radic Biol Med 53:1431-9
Filippidis, Aristotelis S; Zarogiannis, Sotirios G; Randich, Alan et al. (2012) Assessment of locomotion in chlorine exposed mice by computer vision and neural networks. J Appl Physiol 112:1064-72

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