Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM074961-03
Application #
7459566
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
3
Fiscal Year
2007
Total Cost
$2,720,574
Indirect Cost
Name
Emerald Biostructures
Department
Type
DUNS #
016974144
City
Bainbridge Island
State
WA
Country
United States
Zip Code
98110
Christensen, Jeff; Gerdts, Cory J; Clifton, Mathew C et al. (2011) Salvage and storage of infectious disease protein targets in the SSGCID high-throughput crystallization pathway using microfluidics. Acta Crystallogr Sect F Struct Biol Cryst Commun 67:1022-6
Lorimer, Don; Raymond, Amy; Mixon, Mark et al. (2011) Gene Composer in a structural genomics environment. Acta Crystallogr Sect F Struct Biol Cryst Commun 67:985-91
Pompano, Rebecca R; Liu, Weishan; Du, Wenbin et al. (2011) Microfluidics using spatially defined arrays of droplets in one, two, and three dimensions. Annu Rev Anal Chem (Palo Alto Calif) 4:59-81
Li, Liang; Karymov, Mikhail A; Nichols, Kevin P et al. (2010) Dead-end filling of SlipChip evaluated theoretically and experimentally as a function of the surface chemistry and the gap size between the plates for lubricated and dry SlipChips. Langmuir 26:12465-71
Chien, Ellen Y T; Liu, Wei; Zhao, Qiang et al. (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science 330:1091-5
Jaakola, Veli-Pekka; Lane, J Robert; Lin, Judy Y et al. (2010) Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues. J Biol Chem 285:13032-44
Wacker, Daniel; Fenalti, Gustavo; Brown, Monica A et al. (2010) Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. J Am Chem Soc 132:11443-5
Li, Liang; Ismagilov, Rustem F (2010) Protein crystallization using microfluidic technologies based on valves, droplets, and SlipChip. Annu Rev Biophys 39:139-58
Li, Liang; Du, Wenbin; Ismagilov, Rustem F (2010) Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods. J Am Chem Soc 132:112-9
Katritch, Vsevolod; Jaakola, Veli-Pekka; Lane, J Robert et al. (2010) Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem 53:1799-809

Showing the most recent 10 out of 50 publications