In the US, COVID-19 has unveiled a disproportionate health burden in low income and underserved segments of society. In Louisiana, some of the greatest health and economic consequences are evident in our Black communities. There is an urgent need to establish effective testing strategies in these communities as the Fall/Winter virus surges unfold. The Louisiana Clinical and Translational Science (LA CaTS) Center provides the essential infrastructure and key foundational support for biomedical research in our region and is uniquely positioned to lead a community-engaged testing research project to determine differences in COVID-19 testing rates between community-based (churches, community centers, and schools) and medical clinic-based testing sites, and determine approaches that will increase uptake of testing in underserved Black communities in the South. We plan to address these issues using a two-pronged approach. First, we will use a community based participatory research approach to determine differences in SARS-CoV-2 testing rates across distinct types of test sites within five urban underserved Black communities in the American South. We will use a multimedia campaign to promote and conduct RT-PCR testing on salivary samples obtained from 2,000 adults at 1) medical clinics, 2) schools, 3) community centers, and 4) churches (in random order) within five ZIP codes with known low socioeconomic status (SES) and a high representation of Black residents. The primary outcome will be the number of tests performed at each type of test site. We will collect information on age, sex, race, BMI, employment, social determinants of health using an aggregate SES score to identify important correlates of testing rates. Second, we will further leverage our strong and well-integrated partnership with the Baton Rouge Mayor's Healthy City Initiative together with our LA CaTS Community Advisory Boards (CABs) to conduct community-based focus groups to obtain qualitative data about the perceptions and attitudes related to testing access and potential barriers affecting such. We will use this information to determine community-driven approaches that are effective in reducing barriers and create strategies to increase SARS-CoV-2 testing uptake in urban underserved Black communities. Results of this project will greatly increase our understanding of the factors that have led to a disproportionate COVID-19 health burden in these underserved populations and lay the groundwork for developing strategies to reduce these disparities in all underserved Black communities. Resulting data will inform the equitable deployment of future virus/flu testing and a SARS-CoV-2 vaccine.

Public Health Relevance

To date, there has been relatively limited success in implementing COVID-19 testing in large segments of the population, particularly in low income underserved Black communities who concomitantly carry a disproportionate burden of health disparity. The proposed project will determine the best strategy to conduct culturally sensitive COVID-19 testing for urban underserved Black communities in the South. This project will significantly increase our understanding of how to successfully deploy resources that will maximize participation in COVID-19 testing in poor urban underserved Black communities and will lay the groundwork for developing policies to carry out future virus testing and vaccination programs.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54GM104940-05S3
Application #
10258534
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Gao, Hongwei
Project Start
2020-11-17
Project End
2022-06-30
Budget Start
2020-11-17
Budget End
2021-06-30
Support Year
5
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Lsu Pennington Biomedical Research Center
Department
Type
Organized Research Units
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808
Han, Liyuan; Duan, Donghui; Zhang, Shuang et al. (2018) Effects of the interaction between glycated haemoglobin genetic risk score and postpartum weight reduction on glycaemic changes: A gene-weight interaction analysis. Diabetes Obes Metab 20:2733-2739
Fazzino, Tera L; Martin, Corby K; Forbush, Kelsie (2018) The Remote Food Photography Method and SmartIntake App for the Assessment of Alcohol Use in Young Adults: Feasibility Study and Comparison to Standard Assessment Methodology. JMIR Mhealth Uhealth 6:e10460
Halperin, Jason; Butler, Isolde; Conner, Katherine et al. (2018) Linkage and Antiretroviral Therapy Within 72 Hours at a Federally Qualified Health Center in New Orleans. AIDS Patient Care STDS 32:39-41
Burke, Susan J; Batdorf, Heidi M; Martin, Thomas M et al. (2018) Liquid Sucrose Consumption Promotes Obesity and Impairs Glucose Tolerance Without Altering Circulating Insulin Levels. Obesity (Silver Spring) 26:1188-1196
Echeverri, Margarita; Anderson, David; Nápoles, Anna María et al. (2018) Cancer Health Literacy and Willingness to Participate in Cancer Research and Donate Bio-Specimens. Int J Environ Res Public Health 15:
Lovre, Dragana; Shah, Sulay; Sihota, Aanu et al. (2018) Managing Diabetes and Cardiovascular Risk in Chronic Kidney Disease Patients. Endocrinol Metab Clin North Am 47:237-257
Townsend, Janice; Zorek, Joseph A; Andrieu, Sandra C et al. (2018) Developing Interprofessional Education at One U.S. Dental School: Establishing a Baseline and Moving Forward. J Dent Educ 82:446-453
Abu Bakar, Nurulamin; Voermans, Nicol C; Marquardt, Thorsten et al. (2018) Intact transferrin and total plasma glycoprofiling for diagnosis and therapy monitoring in phosphoglucomutase-I deficiency. Transl Res 199:62-76
Lightell Jr, Daniel J; Moss, Stephanie C; Woods, T Cooper (2018) Upregulation of miR-221 and -222 in response to increased extracellular signal-regulated kinases 1/2 activity exacerbates neointimal hyperplasia in diabetes mellitus. Atherosclerosis 269:71-78
Katzmarzyk, Peter T; Most, Jasper; Redman, Leanne M et al. (2018) Energy expenditure and substrate oxidation in White and African American young adults without obesity. Eur J Clin Nutr 72:920-922

Showing the most recent 10 out of 528 publications