Abstract

Many CTR resources and facilities available at UNMC are not currently available at other participating institutions, and vice versa. Resources and facilities will be made mutually available through this KCA, which will help participating institutions and investigators to access critical resources that they lack at present. Annual evaluation activities will assess resource and facilities utilization across the Great Plains IDeA-CTR.
The specific aims are to 1) develop and support the Clinical Research Navigator Office to facilitate access to vital regional clinical research resources; 2) develop and deploy health technologies and tools useful for longitudinal health assessment, early detection, or long-term monitoring of chronic diseases across the lifespan; 3) develop a well-annotated bio-repository to facilitate clinical and translational research (CTR), and expand capacity for bio-repository development; and 4) support and expand existing practice-based research networks to provide a framework for the conduct of CTR to improve health and health outcomes across the Great Plains.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM115458-03
Application #
9525989
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
3
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Kennedy, Sarah G; Smith, Jordan J; Morgan, Philip J et al. (2018) Implementing Resistance Training in Secondary Schools: A Cluster Randomized Controlled Trial. Med Sci Sports Exerc 50:62-72
England, Bryant R; Thiele, Geoffrey M; Anderson, Daniel R et al. (2018) Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications. BMJ 361:k1036
Mohammad, Jiyan; Dhillon, Harsharan; Chikara, Shireen et al. (2018) Piperlongumine potentiates the effects of gemcitabine in in vitro and in vivo human pancreatic cancer models. Oncotarget 9:10457-10469
Koorts, Harriet; Eakin, Elizabeth; Estabrooks, Paul et al. (2018) Implementation and scale up of population physical activity interventions for clinical and community settings: the PRACTIS guide. Int J Behav Nutr Phys Act 15:51
Luan, Haitao; Mohapatra, Bhopal; Bielecki, Timothy A et al. (2018) Loss of the Nuclear Pool of Ubiquitin Ligase CHIP/STUB1 in Breast Cancer Unleashes the MZF1-Cathepsin Pro-oncogenic Program. Cancer Res 78:2524-2535
Mahajan, Tina D; Mikuls, Ted R (2018) Recent advances in the treatment of rheumatoid arthritis. Curr Opin Rheumatol 30:231-237
Duryee, Michael J; Wiese, Benjamin M; Bowman, Jordan R et al. (2018) Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation. Am J Physiol Gastrointest Liver Physiol 314:G418-G430
Bortell, Nikki; Basova, Liana; Najera, Julia A et al. (2018) Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. J Neuroimmune Pharmacol 13:163-178
McLaurin, Elease J; Lee, John D; McDonald, Anthony D et al. (2018) Using Topic Modeling to Develop Multi-level Descriptions of Naturalistic Driving Data from Drivers with and without Sleep Apnea. Transp Res Part F Traffic Psychol Behav 58:25-38
England, Bryant R; Mikuls, Ted R; Curtis, Jeffrey R (2018) Reply. Arthritis Rheumatol 70:320

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