Abstract

The objective of the Immunocytochemistry Core is to support the three research projects of this SCCPRR with high quality, rapid, efficient, and uniform histology of and immunocytochemical localization/expression of specific proteins in the baboon fetal ovary (Project I) and testes (Project II) and human/baboon endometrium (Project III). The immunocytochemistry Core will also provide training for SCCPRR graduate students, postdoctoral fellows, investigators, and technicians in histology and immunocytochemistry.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54HD036207-06A1
Application #
6931413
Study Section
Special Emphasis Panel (ZHD1-DRG-D (29))
Project Start
2004-04-20
Project End
2009-03-31
Budget Start
2004-04-20
Budget End
2005-03-31
Support Year
6
Fiscal Year
2004
Total Cost
$107,252
Indirect Cost

  Institution

Name
University of Maryland Baltimore
Department
Type
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201

  Publications

Pepe, Gerald J; Lynch, Terrie J; Albrecht, Eugene D (2013) Regulation of baboon fetal ovarian development by placental estrogen: onset of puberty is delayed in offspring deprived of estrogen in utero. Biol Reprod 89:132
Bonagura, Thomas W; Zhou, Hui; Babischkin, Jeffery S et al. (2011) Expression of P-450 aromatase, estrogen receptor ? and ?, and ?-inhibin in the fetal baboon testis after estrogen suppression during the second half of gestation. Endocrine 39:75-82
Bonagura, Thomas W; Aberdeen, Graham W; Babischkin, Jeffery S et al. (2010) Divergent regulation of angiopoietin-1 and -2, Tie-2, and thrombospondin-1 expression by estrogen in the baboon endometrium. Mol Reprod Dev 77:430-8
Entezam, Ali; Lokanga, Adihe Rachel; Le, Wei et al. (2010) Potassium bromate, a potent DNA oxidizing agent, exacerbates germline repeat expansion in a fragile X premutation mouse model. Hum Mutat 31:611-6
Albrecht, Eugene D; Pepe, Gerald J (2010) Estrogen regulation of placental angiogenesis and fetal ovarian development during primate pregnancy. Int J Dev Biol 54:397-408
Molitoris, Kristin Happ; Kazi, Armina A; Koos, Robert D (2009) Inhibition of oxygen-induced hypoxia-inducible factor-1alpha degradation unmasks estradiol induction of vascular endothelial growth factor expression in ECC-1 cancer cells in vitro. Endocrinology 150:5405-14
Pepe, Gerald J; Lynch, Terrie J; Davies, William A et al. (2009) Regulation of baboon fetal pituitary prolactin expression by estrogen. Biol Reprod 80:1189-95
Babischkin, Jeffery S; Bonagura, Thomas W; Udoff, Laurence C et al. (2009) Estrogen stimulates the human endometrium to express a factor(s) that promotes vascular smooth muscle cell migration as an early step in microvessel remodeling. Endocrine 35:81-8
Albrecht, Eugene D; Lane, Malcolm V; Marshall, Gary R et al. (2009) Estrogen promotes germ cell and seminiferous tubule development in the baboon fetal testis. Biol Reprod 81:406-14
Rockwell, L Christie; Koos, Robert D (2009) Dexamethasone enhances fertility and preovulatory serum prolactin levels in eCG/hCG primed immature rats. J Reprod Dev 55:247-51

Showing the most recent 10 out of 41 publications