Administrative Core (Core A) The Administrative Core of the Southwestern Comprehensive Sickle Cell Center (the """"""""Center"""""""") is responsible for oversight and coordination of all activities supported by the Center grant. Responsibilities of the Core include submission of annual continuation grants, reports, and responses to queries from NHLBI as well as maintenance of regular contact with senior administrative personnel at the all of the Center sites regarding grants administration, contracts management, human resources, and the components of campus research infrastructures. Given that the Administrative Core of the Center also supports activities in institutions other than the University of Texas Southwestern Medical Center at Dallas, execution of contracts and subcontracts for the delineation of responsibilities and conduct of activities is an important Core function. The Administrative Core is also responsible for oversight of the necessary Center committees, including the Internal Advisory Committee (Executive Committee), External Advisory Committee, Community Advisory Committee, and the committees that are part of the Sickle Cell Scholar Program described in Plan 1. The Administrative Core will continue to be led by the Center Director and PI, Dr. George R. Buchanan, who will serve as """"""""Chief Executive Officer"""""""" of the Center. He will be ably assisted, as in the current grant cycle, by two experienced administrative coordinators, one each at UT Southwestern and Children's Medical Center Dallas. The Administrative Core of the Center is well prepared to serve the national sickle cell community during the 2008-2013 grant cycle.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54HL070588-07
Application #
7880649
Study Section
Special Emphasis Panel (ZHL1)
Project Start
2009-06-25
Project End
2012-01-31
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
7
Fiscal Year
2009
Total Cost
$75,265
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Becker, Amy M; Goldberg, Jordan H; Henson, Michael et al. (2014) Blood pressure abnormalities in children with sickle cell anemia. Pediatr Blood Cancer 61:518-22
Vetter, Courtney L; Buchanan, George R; Quinn, Charles T (2014) Burden of diagnostic radiation exposure in children with sickle cell disease. Pediatr Blood Cancer 61:1322-4
McCavit, Timothy L; Xuan, Lei; Zhang, Song et al. (2013) National trends in incidence rates of hospitalization for stroke in children with sickle cell disease. Pediatr Blood Cancer 60:823-7
McCavit, Timothy L; Quinn, Charles T; Techasaensiri, Chonnamet et al. (2011) Increase in invasive Streptococcus pneumoniae infections in children with sickle cell disease since pneumococcal conjugate vaccine licensure. J Pediatr 158:505-7
Quinn, Charles T; Stuart, Marie J; Kesler, Karen et al. (2011) Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease. Br J Haematol 155:263-7
Becker, Amy M (2011) Sickle cell nephropathy: challenging the conventional wisdom. Pediatr Nephrol 26:2099-109
Neelam, Sudha; Kakhniashvili, David G; Wilkens, Stephan et al. (2011) Functional 20S proteasomes in mature human red blood cells. Exp Biol Med (Maywood) 236:580-91
McCavit, Timothy L; Lin, Hua; Zhang, Song et al. (2011) Hospital volume, hospital teaching status, patient socioeconomic status, and outcomes in patients hospitalized with sickle cell disease. Am J Hematol 86:377-80
Dale, Juanita Conkin; Cochran, Cindy J; Roy, Lonnie et al. (2011) Health-related quality of life in children and adolescents with sickle cell disease. J Pediatr Health Care 25:208-15
Ghatpande, Swati S; Choudhary, Pankaj K; Quinn, Charles T et al. (2010) In vivo pharmaco-proteomic analysis of hydroxyurea induced changes in the sickle red blood cell membrane proteome. J Proteomics 73:619-26

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