The overall clinical goal of the Bronx Comprehensive Sickle Cell Center (BCSCC) is to optimize patient care and the potential for conducting careful research into the pathophysiologic and psychologic manifestations of sickle cell disease that will contribute to the formulation of collaborative biopsychosocial clinical care delivery models based upon scientific evidence and, when needed, expert consensus. To continue the high quality cost-effective management and health care service practices employed in the BCSCC Medical Office and Day Hospital and to extend this care to a larger number of patients.
| Chen, Qiuying; Fabry, Mary E; Rybicki, Anne C et al. (2012) A transgenic mouse model expressing exclusively human hemoglobin E: indications of a mild oxidative stress. Blood Cells Mol Dis 48:91-101 |
| Finnegan, Eileen M; Turhan, Aslihan; Golan, David E et al. (2007) Adherent leukocytes capture sickle erythrocytes in an in vitro flow model of vaso-occlusion. Am J Hematol 82:266-75 |
| Srinivasulu, Sonati; Acharya, A Seetharama; Prabhakaran, Muthuchidambaran et al. (2007) HbS-Savaria: the anti-polymerization effect of a single mutation in human alpha-chains. Protein J 26:523-32 |
| Chen, Qiuying; Lalezari, Iraj; Nagel, Ronald L et al. (2005) Liganded hemoglobin structural perturbations by the allosteric effector L35. Biophys J 88:2057-67 |
| Chen, Qiuying; Vekilov, Peter G; Nagel, Ronald L et al. (2004) Liquid-liquid phase separation in hemoglobins: distinct aggregation mechanisms of the beta6 mutants. Biophys J 86:1702-12 |
| Chen, Qiuying; Bouhassira, Eric E; Besse, Arnaud et al. (2004) Generation of transgenic mice expressing human hemoglobin E. Blood Cells Mol Dis 33:303-7 |
