This proposal describes the career development plan for the proposed Sickle Cell Scholar. The nextgeneration of clinical researchers in sickle cell disease (SCD) will need to include individuals with the skills,attitudes, early research training and experience to capitalize on rapidly developing progress in SCDresearch. In developing this plan, we will use established research infrastructure, including our GraduateTraining Program in Clinical Investigation (GTPCI) at the Johns Hopkins University School of Medicine andJohns Hopkins University Bloomberg School of Public Health and a mentored research project to provideintensive training in clinical research and methodology for the Sickle Cell Scholar.
Our specific aims are: a)To identify, train and develop a creative and successful clinical investigator, with the capability to interactwith, participate in, and lead multidisciplinary teams involved in clinical research, address complex problemsand become a national leader in SCD research; b) To provide the trainee with the requisite skills, knowledge,attitude and experience for a successful career in clinical research in SCD. This training will includeexposure to national and international leaders and curriculum in the multiple disciplines necessary forsuccessful clinical research, including clinical trials design, epidemiology, statistics, research ethics andhuman subjects protection, as well as a research project developed by the Scholar in conjunction with hismentor; c) To provide access to the rich mentoring environment of the Johns Hopkins University School ofMedicine and School of Public Health to provide optimal exposure of the Sickle Cell Scholar to researchexperiences and training. Careful and extensive mentoring will be the cornerstone of this effort, withexposure to and involvement in cutting edge research. Through this program, we ultimately aim to developa Sickle Cell Scholar, who will become a creative, independent investigator, care for patients with SCD andassume a leadership role in SCD patient-oriented research.
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