The Puerto Rico Clinical and Translational Research Consortium (PRCTRC) is an innovative model of collaboration, bringing together and leveraging the intellectual and physical resources of three major medical and health science centers in Puerto Rico: The University of Puerto Rico Medical Sciences Campus (UPRMSC), the Universidad del Caribe Central (UCC), and the Ponce School of Medicine & Health Sciences (PSM&HS) to address and reduce health disparities that most impact Hispanic populations. The mission is to serve as a vital and catalytic element in the efforts to understand, define, and address health disparities in Hispanic populations. Our efforts are guided by four strategic goals: 1) Facilitate the generation and translation of knowledge from the bench into the community by establishing a centralized program focused on reducing health disparities among Hispanic populations; 2) Enhance and support existing training and mentoring programs to increase the number of new minority investigators in Clinical and Translational Research; 3) Encourage collaborations among basic, clinical, and social scientists and community networks and health programs; and 4) Enhance and integrate existing infrastructure for clinical and translational research across Puerto Rico to support and expand Clinical and Translational Research in health disparities The PRCTRC has fostered a synergistic environment that supports research across the clinical and translational research continuum, with an emphasis on four disease states that post the greatest threats to Hispanic health: HIV/AIDS, neurological diseases, cardiovascular and metabolic diseases, and cancer. The PRCTRC provides this integrated infrastructure to investigators through nine Cores: Regulatory Knowledge and Support, Research Design and Biostatistics, clinical Research Resources and Facilities, Technology Resources for Core Laboratories, Biomedical Informatics, Collaborations and Partnerships, Professional Development, Clinical and Translational Pilot Project Program, and Community-based Research. Oversight is provided by an Administrative Core and formative and summative evaluation is provided by an Evaluation Core.

Public Health Relevance

Health disparities among underrepresented minorities constitute an important public health problem. This project proposes to generate important knowledge about the underlying causes and the most effective methods to reduce these health disparities among Hispanics. This project will also increase the participation of underrepresented minority investigators working on this problem.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54MD007587-08
Application #
9478578
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Hailu, Benyam
Project Start
2010-09-17
Project End
2019-04-30
Budget Start
2018-05-01
Budget End
2019-04-30
Support Year
8
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
948108063
City
San Juan
State
PR
Country
United States
Zip Code
Cruz-Correa, Marcia; Hylind, Linda M; Marrero, Jessica Hernandez et al. (2018) Efficacy and Safety of Curcumin in Treatment of Intestinal Adenomas in Patients With Familial Adenomatous Polyposis. Gastroenterology 155:668-673
Peaceman, Alan M; Clifton, Rebecca G; Phelan, Suzanne et al. (2018) Lifestyle Interventions Limit Gestational Weight Gain in Women with Overweight or Obesity: LIFE-Moms Prospective Meta-Analysis. Obesity (Silver Spring) 26:1396-1404
Dirlikov, Emilio; Major, Chelsea G; Medina, Nicole A et al. (2018) Clinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection, Puerto Rico, 2016. JAMA Neurol 75:1089-1097
King, Jamie L; Zhang, Baotong; Li, Yixiang et al. (2018) TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer. Oncogenesis 7:69
Yanik, Elizabeth L; Hernández-Ramírez, Raúl U; Qin, Li et al. (2018) Brief Report: Cutaneous Melanoma Risk Among People With HIV in the United States and Canada. J Acquir Immune Defic Syndr 78:499-504
Joshipura, Kaumudi J; Muñoz-Torres, Francisco J; Dye, Bruce A et al. (2018) Longitudinal association between periodontitis and development of diabetes. Diabetes Res Clin Pract 141:284-293
Guerrero-Ramírez, Grace; Cumba-Avilés, Eduardo (2018) Factors Associated with Suicidal Ideation and Quality of Life in Adolescents from Puerto Rico with Type 1 Diabetes. P R Health Sci J 37:19-21
Amaro-Rivera, Kiara; López-Cepero, Andrea; Diaz, Beatriz et al. (2018) Micronutrient Intake and the Contribution of Dietary Supplements in Hispanic Infants. J Diet Suppl 15:129-139
Gonzalez-Mercado, Velda J; Fridley, Brooke L; Saligan, Leorey N (2018) Sestrin family of genes and their role in cancer-related fatigue. Support Care Cancer 26:2071-2074
Capó-Vélez, Coral M; Morales-Vargas, Bryan; García-González, Aurian et al. (2018) The alpha7-nicotinic receptor contributes to gp120-induced neurotoxicity: implications in HIV-associated neurocognitive disorders. Sci Rep 8:1829

Showing the most recent 10 out of 285 publications