Achieving ?ola? (health in Hawaiian) for the communities suffering disproportionately from genetic, environmental and socioeconomic disparities in health is the rationale for the proposed RCMI Specialized Center at the University of Hawaii at Manoa. The objective of the Center, named Ola HAWAII, is to grow and support a community of health disparities investigators (the ?workforce?) to harness the power of diverse thought (the ?thinkforce?) to determine the causes of and interventions for health disparities. The Center's objective will be achieved by the following specific aims.
Specific Aim 1 : Foster and facilitate the conduct of high-impact team-science research addressing health disparities. Plan: Involve all stakeholders in decision-making process of selecting meritorious project proposals and provide funding and infrastructure support for scientifically rigorous R01/R21-type basic biomedical, behavioral and clinical research projects on health disparities. Promote collaborations and partnerships with other RCMI grantee institutions through the RCMI Translational Research Network (RTRN).
Specific Aim 2 : Strengthen and diversify the basic biomedical, behavioral and clinical research workforce and thinkforce focusing on health disparities. Plan. Identify the most motivated basic biomedical, behavioral and clinical faculty, particularly those from underrepresented backgrounds, for careers in health disparities research. Identify senior faculty to serve on mentoring teams for new and early-stage investigators. Implement a Team-Science Mentoring Bootcamp for personalized education and skills training. Implement a Team-Science Pilot Projects Program to provide funding, on a competitive basis, to new and early-stage investigators to generate data for grant applications.
Specific Aim 3 : Enhance, consolidate and sustain core facilities and resources for health disparities research. Plan. Implement objective criteria and metrics to evaluate core needs and usage, core-dependent research productivity, and revenue generation. Consolidate core resources to reduce redundancies. Provide modest funding through a ?CoreBucks? Program to maximize utilization of core resources and services across RTRN. Institutional investments will ensure the sustainability of the proposed RCMI Specialized Center to provide the infrastructure and resources for a new era of research excellence on the science of health disparities.

Public Health Relevance

Ola HAWAII is a proposed RCMI Specialized Center at the University of Hawaii at Manoa designed to advance ?ola? (health in Hawaiian) for communities experiencing health disparities. It is intended to support health disparities investigators and community partners (the ?workforce?) to harness the power of diverse thought (the ?thinkforce?) to determine the causes of and interventions for health disparities in Hawaii. There are three specific aims: (1) Foster and facilitate the conduct of high-impact team-science research addressing health disparities; (2) Strengthen and diversify the basic biomedical, behavioral and clinical research workforce and thinkforce focusing on health disparities; and (3) Enhance, consolidate and sustain core facilities and resources for health disparities research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54MD007601-32
Application #
9569294
Study Section
Special Emphasis Panel (ZMD1)
Program Officer
Berzon, Richard
Project Start
1997-09-01
Project End
2022-06-30
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
32
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Hawaii
Department
Type
Schools of Medicine
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Hsu, Denise C; Sunyakumthorn, Piyanate; Wegner, Matthew et al. (2018) Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques. J Virol 92:
Hu, Ling; Zhang, Rong; Yuan, Qiong et al. (2018) The emerging role of microRNA-4487/6845-3p in Alzheimer's disease pathologies is induced by A?25-35 triggered in SH-SY5Y cell. BMC Syst Biol 12:119
Oeser, Steffen G; Bingham, Jon-Paul; Collier, Abby C (2018) Regulation of Hepatic UGT2B15 by Methylation in Adults of Asian Descent. Pharmaceutics 10:
Siriwardhana, Chathura; Lim, Eunjung; Aggarwal, Lovedhi et al. (2018) Racial/Ethnic and County-level Disparity in Inpatient Utilization among Hawai'i Medicaid Population. Hawaii J Med Public Health 77:103-113
Berry, Marla; Chen, John; Hixon, Alan et al. (2018) Medical School Hotline: School of Medicine Departments - Year in Review 2017, Part 1. Hawaii J Med Public Health 77:14-16
D'Antoni, Michelle L; Byron, Mary Margaret; Chan, Phillip et al. (2018) Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities. J Infect Dis 218:1453-1463
Laenen, Lies; Vergote, Valentijn; Kafetzopoulou, Liana Eleni et al. (2018) A Novel Hantavirus of the European Mole, Bruges Virus, Is Involved in Frequent Nova Virus Coinfections. Genome Biol Evol 10:45-55
Jiang, Zhenhuan; Jiang, Jiannong; Zhao, Bizeng et al. (2018) CPNE1 silencing inhibits the proliferation, invasion and migration of human osteosarcoma cells. Oncol Rep 39:643-650
Lim, Eunjung; Gandhi, Krupa; Siriwardhana, Chathura et al. (2018) Racial and ethnic differences in mental health service utilization among the Hawaii medicaid population. J Ment Health :1-10
Gong, Ting; Torres, Daniel J; Berry, Marla J et al. (2018) Hypothalamic redox balance and leptin signaling - Emerging role of selenoproteins. Free Radic Biol Med 127:172-181

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