ADMINISTRATION/MANAGEMENT CORE (AIM)A/M Aims 1. Communication (Internal and External). A/M will: i) hold regular Center meetings to discusspriorities of the Center and use the meetings to update and educate one another regarding activities of theindividual cores; ii) continue our outreach effort, focusing on building collaborations for developing targetsunique to multiplex and/or high content analysis in flow cytometry with a submission of a target for each R03cycle; iii) organize productive partnerships, in particular those opportunities that allow HT flow cytometry toreach its potential in novel applications and technological advancement; and iv) if requested by MLPCN,constitute an Advisory Board to meet in conjunction with our annual Roadmap Symposium in 3rd quarter(Spring) of each year. Meeting agendas are set with each participant contacted in advance to insure efficientmeeting process. Innovation: Laboratory results and meeting summaries are posted to the Center Wiki.2. Operations (Budget, Personnel, Reporting to NIH, Co-ordination within UNM). A/M will: i) be responsible forannual reporting to NIH as well as monthly tracking reports; ii) order and receive SMR shipments and makethese available for screening under the director of the Chemical Biologist in HTS/I; iii) represent the Center atMLPCN Steering Committee Meetings and insure representation at monthly working group teleconferences.;iv) organize and prioritize the budget, prepare supplements, manage service contracts; v) prioritize, fill, andtrain staff positions in the Center; vi) co-ordinate within UNM regarding human resource policies andprocedures, institutional space policies, etc.3. Work Flow Management: A/M will: i) organize target teams across the cores; ii) standardize protocols, andoversee probe development plans, probe and final reports, and other documentation as needed.; and iii)manage a portfolio of cell and bead-based molecular target assays through the UNMCMD pipeline andevaluate and implement the overall opportunities of the portfolio for biological impact. Agendas are set for eachtarget team meeting with each participant contacted in advance to insure efficient meeting process. Meetingsummaries are posted to the Center Wiki.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54MH084690-01
Application #
7637652
Study Section
Special Emphasis Panel (ZRG1-IFCN-K (52))
Project Start
2008-09-01
Project End
2014-05-31
Budget Start
2008-09-01
Budget End
2009-05-31
Support Year
1
Fiscal Year
2008
Total Cost
$686,863
Indirect Cost
Name
University of New Mexico Health Sciences Center
Department
Type
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Palsuledesai, Charuta C; Surviladze, Zurab; Waller, Anna et al. (2018) Activation of Rho Family GTPases by Small Molecules. ACS Chem Biol 13:1514-1524
Bredemeyer, Andrea L; Edwards, Bruce S; Haynes, Mark K et al. (2018) High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining. SLAS Discov 23:624-633
Wu, Yang; Stauffer, Shaun R; Stanfield, Robyn L et al. (2016) Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. J Biomol Screen 21:74-87
Yang, Jeremy J; Ursu, Oleg; Lipinski, Christopher A et al. (2016) Badapple: promiscuity patterns from noisy evidence. J Cheminform 8:29
Zahoránszky-K?halmi, Gergely; Bologa, Cristian G; Oprea, Tudor I (2016) Impact of similarity threshold on the topology of molecular similarity networks and clustering outcomes. J Cheminform 8:16
Hong, Lin; Chavez, Stephanie; Smagley, Yelena et al. (2016) Relationship of light scatter change and Cdc42-regulated actin status. Cytometry B Clin Cytom 90:499-505
Sykes, David B; Kfoury, Youmna S; Mercier, François E et al. (2016) Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell 167:171-186.e15
Holmes, Ann R; Cardno, Tony S; Strouse, J Jacob et al. (2016) Targeting efflux pumps to overcome antifungal drug resistance. Future Med Chem 8:1485-501
Hong, Lin; Guo, Yuna; BasuRay, Soumik et al. (2015) A Pan-GTPase Inhibitor as a Molecular Probe. PLoS One 10:e0134317
Guo, Yuna; Kenney, S Ray; Muller, Carolyn Y et al. (2015) R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis. Mol Cancer Ther 14:2215-27

Showing the most recent 10 out of 113 publications