This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The objective of the Administrative Core is to provide administrative and fiscal support for all activities of the Pacific Research Center for Early Human Development (PRCEHD or Center). Under the direction of Kenneth Ward, MD, the Administrative core will facilitate establishment of laboratories, acquisition of equipment, staff and other resources, coordinating with the PI and the Internal Advisory Committee (IAC) to ensure that operations run smoothly. The Administrative Core will support management of the proposed research program, and will actively seek opportunities to further build research capacity in early human development research. By maintaining compliance with all applicable, federal and state guidelines and University of Hawai`i regulations, the Administrative Core will ensure that all PRCEHD activities take place within an environment that meets and exceeds applicable standards for research. This will include review of ethical and scientific issues to foster research that is scientifically rigorous and ethically acceptable. The Administrative Core will foster direct communication between the Dean of the John A. Burns School of Medicine (JABSOM) and the PRCEHD to ensure that the Center forges ahead in a direction that is consistent with JABSOM's long-term goals. In addition, the Administrative Core will serve as a link between all cores, and all entities involved, including JABSOM's Molecular Endocrinology Laboratory, Department of Obstetrics and Gynecology and Women's Health (JABSOM Ob/Gyn), the Department of Pediatrics, the Clinical Research Center (CRC), the Kapiolani Medical Center for Women and Children (KMCWC), the Institute of Biogenesis Research (IBR), The University of Utah Department of Obstetrics and Gynecology (Utah Ob/Gyn), and the Community (Collectively, the Partners). The Administrative Core will facilitate communications and meetings to enable the Center's Partners, investigators, mentors and staff to collaborate efficiently and effectively in accomplishing the Center's goals. In sum, the Administrative Core will provide support for coordination, planning, implementation and evaluation of all Center activities.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54RR014607-10
Application #
7724698
Study Section
Special Emphasis Panel (ZRR1-RI-1 (01))
Project Start
2008-08-01
Project End
2009-07-31
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
10
Fiscal Year
2008
Total Cost
$490,990
Indirect Cost
Name
University of Hawaii
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Riangwiwat, Tanawan; Kohorn, Lindsay B; Chow, Dominic C et al. (2016) CD4/CD8 Ratio Predicts Peripheral Fat in HIV-Infected Population. J Acquir Immune Defic Syndr 72:e17-9
Wright, Tricia E; Schuetter, Renee; Tellei, Jacqueline et al. (2015) Methamphetamines and pregnancy outcomes. J Addict Med 9:111-7
Burlingame, J; Horiuchi, B; Ohana, P et al. (2012) The contribution of heart disease to pregnancy-related mortality according to the pregnancy mortality surveillance system. J Perinatol 32:163-9
Horton, J S; Yamamoto, S Y; Bryant-Greenwood, G D (2012) Relaxin augments the inflammatory IL6 response in the choriodecidua. Placenta 33:399-407
Hiraoka, Mark; Urschitz, Johann; Sultan, Omar et al. (2011) A polymorphism in the retinol binding protein 4 gene is not associated with gestational diabetes mellitus in several different ethnic groups. Hawaii Med J 70:164-7
Horton, J S; Yamamoto, S Y; Bryant-Greenwood, G D (2011) Relaxin modulates proinflammatory cytokine secretion from human decidual macrophages. Biol Reprod 85:788-97
Wright, T E; Milam, K A; Rougee, L et al. (2011) Agreement of umbilical cord drug and cotinine levels with maternal self-report of drug use and smoking during pregnancy. J Perinatol 31:324-9
Kendal-Wright, C E; Hubbard, D; Gowin-Brown, J et al. (2010) Stretch and inflammation-induced Pre-B cell colony-enhancing factor (PBEF/Visfatin) and Interleukin-8 in amniotic epithelial cells. Placenta 31:665-74
Urschitz, Johann; Kawasumi, Miyuri; Owens, Jesse et al. (2010) Helper-independent piggyBac plasmids for gene delivery approaches: strategies for avoiding potential genotoxic effects. Proc Natl Acad Sci U S A 107:8117-22
Wright, Tricia E; Tam, Elizabeth (2010) Disparate rates of persistent smoking and drug use during pregnancy of women of Hawaiian ancestry. Ethn Dis 20:S1-215-8

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