In continuing its Body Composition and Metabolic Core and related laboratory, Drew proposes to improve the health of individuals?especially racial and ethnic minorities?suffering obesity and metabolic disorders. This core will further augment and strengthen the institutional clinical research capabilities to support diabetes-related research studies by providing metabolic and nutritional services to Drew investigators. The populations served by Drew, primarily Hispanic and African American, suffer from higher rates of obesity, diabetes, metabolic syndrome, and physical inactivity, all of which add to the high morbidity and mortality rate in this community. This core will provide centralized access to facilities and equipment for body composition assessment in these populations, enhance the research capabilities and competitiveness of Drew investigators currently engaged in metabolic research, and facilitate recruitment of investigators with expertise in state-of-the-art metabolic and body composition methodology and a commitment to diabetes and metabolic research.
The specific aims of this core are to: 1. Provide centralized access via a laboratory to facilities and equipment for body composition assessment in humans; 2. Enhance research capabilities and competitiveness of Drew investigators currently engaged in metabolic research; 3. Facilitate recruitment of investigators with expertise in state-of-the art metabolic and body composition methodology, as well as a commitment to diabetes and metabolic research; and 4. Increase the body of knowledge and research activity (grant submissions and procurement, presentations and publications) in diabetes and metabolic disorders as related to improving the health care of women, ethnic/racial minorities, and other disadvantaged populations.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
2U54RR014616-06
Application #
6970516
Study Section
Special Emphasis Panel (ZRR1-RI-1 (01))
Project Start
2004-09-23
Project End
2005-07-31
Budget Start
2004-09-23
Budget End
2005-07-31
Support Year
6
Fiscal Year
2004
Total Cost
$459,502
Indirect Cost
Name
Charles R. Drew University of Medicine & Science
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059
Ren, Xiuhai; Lutfy, Kabirullah; Mangubat, Michael et al. (2013) Alterations in phosphorylated CREB expression in different brain regions following short- and long-term morphine exposure: relationship to food intake. J Obes 2013:764742
Tweed, Jesse Oliver; Hsia, Stanley H; Lutfy, Kabirullah et al. (2012) The endocrine effects of nicotine and cigarette smoke. Trends Endocrinol Metab 23:334-42
Hsia, Stanley H (2011) Insulin glargine compared to NPH among insulin-naïve, U.S. inner city, ethnic minority type 2 diabetic patients. Diabetes Res Clin Pract 91:293-9
Hsia, Stanley H; Navar, Maria D; Duran, Petra et al. (2011) Sitagliptin compared with thiazolidinediones as a third-line oral antihyperglycemic agent in type 2 diabetes mellitus. Endocr Pract 17:691-8
Vuong, Cassidy; Van Uum, Stan H M; O'Dell, Laura E et al. (2010) The effects of opioids and opioid analogs on animal and human endocrine systems. Endocr Rev 31:98-132
Calderón, José Luis; Bazargan, Mohsen; Sangasubana, Nisaratana et al. (2010) A comparison of two educational methods on immigrant Latinas breast cancer knowledge and screening behaviors. J Health Care Poor Underserved 21:76-90
Davidson, Mayer B; Schriger, David L (2010) Effect of age and race/ethnicity on HbA1c levels in people without known diabetes mellitus: implications for the diagnosis of diabetes. Diabetes Res Clin Pract 87:415-21
Jones, Loretta; Lu, Michael C; Lucas-Wright, Aziza et al. (2010) One Hundred Intentional Acts of Kindness toward a Pregnant Woman: building reproductive social capital in Los Angeles. Ethn Dis 20:S2-36-40
Kilimnik, German; Kim, Abraham; Steiner, Donald F et al. (2010) Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic ?-cells in mouse models of ß-cell regeneration. Islets 2:149-55
Anghel, A; Jamieson, C A M; Ren, X et al. (2010) Gene expression profiling following short-term and long-term morphine exposure in mice uncovers genes involved in food intake. Neuroscience 167:554-66

Showing the most recent 10 out of 116 publications