This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator.
SPECIFIC AIMS Charles Drew University of Medicine and Science (CDU) will continue to enhance its Clinical Center for Research Excellence (CCRE) activities through the specialized """"""""Center of Urban Research and Education in Diabetes and Metabolism"""""""" (CUREDM). The purposes guiding the center's activities are to increase the critical mass of research scientists engaged in clinical research and to increase diabetes and metabolic-related clinical research conducted at Drew. Diabetes is one of the key focus areas of Healthy People 2010, the blueprint for the nation's health agenda. In addition, the unique patient population at Drew University?comprised of approximately 54 percent Hispanics, 34 percent African Americans, 7 percent whites, and 5 percent Asian/Pacific Islanders?suffers disproportionately from diabetes and metabolic-related disorders. The overall specific aims for this application are: 1.To increase the critical mass of diabetes and metabolic-related clinical researchers; 2.To promote faculty development through the support of mentored-research pilot projects by pairing dedicated senior investigators with promising junior faculty; 3.To enhance the careers of junior investigators by providing an environment that facilitates scientific discovery and short-term curricula and/or formal degree training at Drew University; 4.To improve diabetes and metabolic disorder patient outcomes in the context of methodologically rigorous clinical research through two innovative research cores: 1) The Translational Research Core, which will collaborate with Drew's research-intensive partner, UCLA;and 2) the Body Composition and Metabolism Core;and 5.To increase the body of knowledge and research activity (grant submissions and procurement, presentations, and publications), especially in diabetes and metabolic disorders as they relate to improving the health care of women, ethnic/racial minorities, and other disadvantaged populations.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54RR014616-10S1
Application #
7961295
Study Section
Special Emphasis Panel (ZRR1-RI-1 (01))
Project Start
2009-09-25
Project End
2009-09-30
Budget Start
2009-09-25
Budget End
2009-09-30
Support Year
10
Fiscal Year
2009
Total Cost
$102,259
Indirect Cost
Name
Charles R. Drew University of Medicine & Science
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059
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Tweed, Jesse Oliver; Hsia, Stanley H; Lutfy, Kabirullah et al. (2012) The endocrine effects of nicotine and cigarette smoke. Trends Endocrinol Metab 23:334-42
Hsia, Stanley H (2011) Insulin glargine compared to NPH among insulin-naïve, U.S. inner city, ethnic minority type 2 diabetic patients. Diabetes Res Clin Pract 91:293-9
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Davidson, Mayer B; Schriger, David L (2010) Effect of age and race/ethnicity on HbA1c levels in people without known diabetes mellitus: implications for the diagnosis of diabetes. Diabetes Res Clin Pract 87:415-21
Jones, Loretta; Lu, Michael C; Lucas-Wright, Aziza et al. (2010) One Hundred Intentional Acts of Kindness toward a Pregnant Woman: building reproductive social capital in Los Angeles. Ethn Dis 20:S2-36-40
Kilimnik, German; Kim, Abraham; Steiner, Donald F et al. (2010) Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic ?-cells in mouse models of ß-cell regeneration. Islets 2:149-55
Anghel, A; Jamieson, C A M; Ren, X et al. (2010) Gene expression profiling following short-term and long-term morphine exposure in mice uncovers genes involved in food intake. Neuroscience 167:554-66
Chen, John; Patel, Roshni; Friedman, Theodore C et al. (2010) The Behavioral and Pharmacological Actions of NMDA Receptor Antagonism are Conserved in Zebrafish Larvae. Int J Comp Psychol 23:82-90

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