Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Project Title: Dose Response Effects of Aerobic Exercise on Insulin Sensitivity and the Metabolic Syndrome SPECIFIC AIMS This project has three specific aims: To compare the effects of a mild- versus moderate-intensity, supervised, six-month aerobic exercise program on the extent of change and the lag-time required to detect a change in various parameters associated with the metabolic syndrome in high-risk, non-diabetic subjects with the metabolic syndrome To examine the longer-term exercise adherence of subjects under free-living, unsupervised conditions following a six-month supervised exercise program, at an accessible community-based exercise facility To establish a career development platform for the principal investigator in the area of exercise physiology and the therapeutic utility of aerobic exercise for the metabolic syndrome

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54RR014616-10S1
Application #
7961298
Study Section
Special Emphasis Panel (ZRR1-RI-1 (01))
Project Start
2009-09-25
Project End
2009-09-30
Budget Start
2009-09-25
Budget End
2009-09-30
Support Year
10
Fiscal Year
2009
Total Cost
$55,443
Indirect Cost

  Institution

Name
Charles R. Drew University of Medicine & Science
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
785877408
City
Los Angeles
State
CA
Country
United States
Zip Code
90059

  Publications

Ren, Xiuhai; Lutfy, Kabirullah; Mangubat, Michael et al. (2013) Alterations in phosphorylated CREB expression in different brain regions following short- and long-term morphine exposure: relationship to food intake. J Obes 2013:764742
Tweed, Jesse Oliver; Hsia, Stanley H; Lutfy, Kabirullah et al. (2012) The endocrine effects of nicotine and cigarette smoke. Trends Endocrinol Metab 23:334-42
Hsia, Stanley H (2011) Insulin glargine compared to NPH among insulin-naïve, U.S. inner city, ethnic minority type 2 diabetic patients. Diabetes Res Clin Pract 91:293-9
Hsia, Stanley H; Navar, Maria D; Duran, Petra et al. (2011) Sitagliptin compared with thiazolidinediones as a third-line oral antihyperglycemic agent in type 2 diabetes mellitus. Endocr Pract 17:691-8
Calderón, José Luis; Bazargan, Mohsen; Sangasubana, Nisaratana et al. (2010) A comparison of two educational methods on immigrant Latinas breast cancer knowledge and screening behaviors. J Health Care Poor Underserved 21:76-90
Davidson, Mayer B; Schriger, David L (2010) Effect of age and race/ethnicity on HbA1c levels in people without known diabetes mellitus: implications for the diagnosis of diabetes. Diabetes Res Clin Pract 87:415-21
Jones, Loretta; Lu, Michael C; Lucas-Wright, Aziza et al. (2010) One Hundred Intentional Acts of Kindness toward a Pregnant Woman: building reproductive social capital in Los Angeles. Ethn Dis 20:S2-36-40
Kilimnik, German; Kim, Abraham; Steiner, Donald F et al. (2010) Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic ?-cells in mouse models of ß-cell regeneration. Islets 2:149-55
Anghel, A; Jamieson, C A M; Ren, X et al. (2010) Gene expression profiling following short-term and long-term morphine exposure in mice uncovers genes involved in food intake. Neuroscience 167:554-66
Chen, John; Patel, Roshni; Friedman, Theodore C et al. (2010) The Behavioral and Pharmacological Actions of NMDA Receptor Antagonism are Conserved in Zebrafish Larvae. Int J Comp Psychol 23:82-90

Showing the most recent 10 out of 116 publications