Abstract

This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The TCNP training effort will be spearheaded by Jonathan Pevsner of Johns Hopkins University School of Medicine (Dr. Pevsner''''''''s primary appointment is with the nearby Kennedy Krieger Institute), a recognized expert in Bioinformatics. Dr. Pevsner will devote considerable time to organizing an introductory graduate level course in Proteomics to complement an extensive menu of existing coursework in Biochemistry, Computational Biology and Bioinformatics. In addition, a high-level course in 'Protein interaction networks and pathways' will be developed under this core by Drs. Bader and Levchenko (see Core 3 above

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54RR020839-05
Application #
7724695
Study Section
Special Emphasis Panel (ZRG1-BST-D (55))
Project Start
2008-08-01
Project End
2009-07-31
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
5
Fiscal Year
2008
Total Cost
$42,156
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Uzoma, Ijeoma; Hu, Jianfei; Cox, Eric et al. (2018) Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration. Mol Cell Proteomics 17:871-888
Cox, Eric; Hwang, Woochang; Uzoma, Ijeoma et al. (2017) Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex. Mol Cell Proteomics 16:812-823
Newman, Heather A; Meluh, Pamela B; Lu, Jian et al. (2017) A high throughput mutagenic analysis of yeast sumo structure and function. PLoS Genet 13:e1006612
Noren, David P; Chou, Wesley H; Lee, Sung Hoon et al. (2016) Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses. Sci Signal 9:ra20
Liu, Shuang; Zhang, Hongyan; Dai, Jun et al. (2015) Characterization of monoclonal antibody's binding kinetics using oblique-incidence reflectivity difference approach. MAbs 7:110-9
Cubeñas-Potts, Caelin; Srikumar, Tharan; Lee, Christine et al. (2015) Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes. Proteomics 15:763-72
Zhong, Jun; Martinez, Marissa; Sengupta, Srona et al. (2015) Quantitative phosphoproteomics reveals crosstalk between phosphorylation and O-GlcNAc in the DNA damage response pathway. Proteomics 15:591-607
Tu, Shun; Guo, Shu-Juan; Chen, Chien-Sheng et al. (2015) YcgC represents a new protein deacetylase family in prokaryotes. Elife 4:
Taylor, Martin S; Dempsey, Daniel R; Hwang, Yousang et al. (2015) Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs. Bioorg Chem 62:64-73
Huang, Tai-Chung; Cutler, Jevon; Bharne, Shubhada et al. (2015) Integrated analysis of CRLF2 signaling in acute lymphoblastic leukemia identifies Polo-like kinase 1 as a potential therapeutic target. Leuk Lymphoma 56:1524-7

Showing the most recent 10 out of 219 publications