This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Core 2 develops tools to facilitate and extend the research efforts made by investigators in computational biology and biomedical computing, including those involved in Core 3 (as shown in Figure 2-1). We have classified these tools into threecategories:1. Data Analysis: mathematical andcomputational methods that solve specificproblems faced by biomedical investigators.2. User Interaction: methods by whichinvestigators can interact with both data andalgorithms.3. Knowledge Management: management of information about investigators, projects, programs, and data. This includes automated methods for data access control, file format translation, data provenance, tracking and program execution requirements.Each tool is of interest in its own right, and each tool is revisited in each of four major subsections:A.
Specific Aims B. Background and SignificanceC. Preliminary StudiesD. Design and Methods.Before describing the tools themselves, it is pertinent to introduce the larger framework into which these tools are integrated. We refer to this framework as a computational atlas.
Showing the most recent 10 out of 309 publications