EXCEED THE SPACEPROVIDED. The ultimate test our nation's biomedical system is its capacity to draw upon the full breadth of talent ofAmerica's diverse population and care for the most vulnerable elements of our society. The dual-edgedproblems of ethnic disparities in health and the under-representation of minority clinical investigators areamong the most glaring failures of our biomedical enterprise. The Morehouse School of Medicine (MSM) isuniquely poised to provide leadership in redressing these problems and contribute to the fulfillment of theNIH Roadmap's plan to re-engineer the clinical research enterprise for the 21st century. MSM's President, Dr. David Satcher (the 16th US Surgeon General), is committed to the goal ofestablishing the MSM as one of the preeminent centers of excellence in research that addresses the burdenof health disparities. The proposed CCRE research program will be a critical element of the institution'sstrategic plan to continue the successful expansion of our translational and patient-oriented researchportfolio. The major objective of this program focuses on establishing a research infrastructure that willfoster the successful development of a cadre of junior clinical investigators into future leaders of the clinicalresearch enterprise. This CCRE program will build upon MSM's recent trajectory of success in enhancing itsresearch portfolio by pursuing the following specific aims:
Aim I. To establish an organizational framework for promoting a collaborative, inter-disciplinary approachto clinical investigation that engages the full breadth of the MSM scientific community and creates a nurturingresearch environment for the development of MSM's junior faculty.
Aim II. To establish an institution-wide mechanism to recruit and mentor a critical mass of talented youngfaculty who will develop successful translational and clinical research programs at MSM.
Aim 1 11. To recruit a 'magnet investigator' who will provide ongoing leadership of the CCRE program,further enhance MSM's research capacity and expand the critical mass of senior clinician-scientist mentors.
Aim I V. To establish a vibrant, collaborative research infrastructure that supports a continual process ofinnovation in clinical investigation by the ongoing incorporation of new enabling technologies in translationaland patient-oriented research.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54RR022814-03
Application #
7256538
Study Section
Special Emphasis Panel (ZRR1-RI-4 (01))
Program Officer
Beanan, Maureen J
Project Start
2005-09-30
Project End
2010-06-30
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
3
Fiscal Year
2007
Total Cost
$876,287
Indirect Cost
Name
Morehouse School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Ofili, Elizabeth O; Pemu, Priscilla E; Quarshie, Alexander et al. (2018) DEMOCRATIZING DISCOVERY HEALTH WITH N=Me. Trans Am Clin Climatol Assoc 129:215-234
Van Dyke, Miriam E; Vaccarino, Viola; Dunbar, Sandra B et al. (2017) Socioeconomic status discrimination and C-reactive protein in African-American and White adults. Psychoneuroendocrinology 82:9-16
Van Dyke, Miriam E; Vaccarino, Viola; Quyyumi, Arshed A et al. (2016) Socioeconomic status discrimination is associated with poor sleep in African-Americans, but not Whites. Soc Sci Med 153:141-7
Morris, Alanna A; Patel, Riyaz S; Binongo, Jose Nilo G et al. (2013) Racial differences in arterial stiffness and microcirculatory function between Black and White Americans. J Am Heart Assoc 2:e002154
Vivar, Juan C; Pemu, Priscilla; McPherson, Ruth et al. (2013) Redundancy control in pathway databases (ReCiPa): an application for improving gene-set enrichment analysis in Omics studies and ""Big data"" biology. OMICS 17:414-22
Ofori-Acquah, Solomon F; Buchanan, Iris D; Osunkwo, Ifeyinwa et al. (2012) Elevated circulating angiogenic progenitors and white blood cells are associated with hypoxia-inducible angiogenic growth factors in children with sickle cell disease. Anemia 2012:156598
Patel, Riyaz S; Morris, Alanna A; Ahmed, Yusuf et al. (2012) A genetic risk variant for myocardial infarction on chromosome 6p24 is associated with impaired central hemodynamic indexes. Am J Hypertens 25:797-803
Pemu, Priscilla E; Anderson, Leonard; Gee, Beatrice E et al. (2012) Early alterations of the immune transcriptome in cultured progenitor cells from obese African-American women. Obesity (Silver Spring) 20:1481-90
Morris, Alanna Amyre; Zhao, Liping; Ahmed, Yusuf et al. (2011) Association between depression and inflammation--differences by race and sex: the META-Health study. Psychosom Med 73:462-8
Lapu-Bula, Rigobert; Onwuanyi, Anekwe; Bielo, Marie-Vero et al. (2011) Risk factors for acute non-ST-segment elevation myocardial infarction in a population sample of predominantly African American patients with chest pain and normal coronary arteries. Ethn Dis 21:421-8

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