The ultimate goals of the University of Chicago CTSA program are to train scientists and health careproviders at the University, our partner institutions, and our Community to determine the molecularunderpinnings of disease or disease predisposition in any individual patient; to develop, test, implement, andmake readily available to residents in our Community personalized therapies directed toward those individualunderpinnings; and to do this in a way that is rigorous, valid, efficient, ethical, and respectful of ourCommunity's needs and values. In a robust alliance with Argonne National Laboratory, the Illinois Institute ofTechnology, and two large healthcare organizations, we will undertake three bold new steps that willtransform clinical and translational research at our institutions and in our Community: 1) Creation of anInstitute for Translational Medicine, a new University-wide structure to collect, integrate, and disseminate theintellectual, organizational, and resource infrastructure needed to promote and support multidisciplinarytranslational research collaborations; 2) Synergistic research interaction with a new UC Urban HealthInitiative which, through partnership with Community stakeholders, aims to improve Community health careaccess and quality, to build health literacy and trust throughout the Community, to enhance a translationalresearch program informed by and responsive to the needs of the Community, and so to reduce healthdisparities; and 3) Establishment of a new academic Committee on Clinical and Translational Science and ofmultiple novel training programs to encourage and develop careers in clinical and translational research,intended for high school students through university faculty and across the entire translational researchspectrum. Our consortium of dedicated CTSA investigators will employ a systems medicine approach toleverage their particular expertise in social science, genetic medicine, and integrative therapeutics. Together,this team and these transforming innovations will allow the University of Chicago CTSA to prepare the nextgeneration of clinical and translational researchers to realize our vision of widely available, effective, andpersonalized therapies that find everyday application in Community practice and thereby reduce healthdisparities in diverse adult and pediatric populations.
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