Entering its fifth year, the Johns Hopkins Institute for Clinical and Translational Research (ICTR) is dedicated to creating a new model for conducting clinical and translational research throughout the Johns Hopkins University, by addressing critical obstacles that impede the progress of basic science discoveries to the clinic, and clinical discoveries into the community. By encouraging and catalyzing change, the ICTR seeks to lower barriers between scientific disciplines, foster collaboration, and. provide creative, innovative approaches to the solution of complex medical problems. Through the national consortium of CTSA institutions, the ICTR also participates in the advancement of Clinical and Translational Research as an academic discipline. The ICTR offers a wide variety of consulting, educational, training, infrastructure and support services to any and all members ofthe Johns Hopkins research community who are currently preparing or executing a study. The ICTR supports adult inpatient/outpatient, child inpatient/outpatient clinical reseach units at both the Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center. The ICTR provides support for investigators from early Tl translation (Drug Development, Geneomics and Proteomics Translational Cores) to final phases of T2 translation (Community Engagement and Knowledge Implementation Programs). Protecting human research participants in the broadest sense is essential to the mission of translational research so the ICTR supports research participant advocates and regulatory knowledge program that has the primary role of research ethics training at Johns Hopkins. Delays in getting pilot funding is a huge barrier to accelerating the pace of translational research. In response we have created an Accelerated Translational Incubator Program (ATIP) which funds translational teams for a milestone driven, project managed one year period of time. The ICTR has created the Johns Hopkins Clinical Research Network (JHCRN) with 11 hospitals (including 6 non Johns Hopkins Hospitals). The JHCRN includes written agreements to improve the efficiency of study startup. Finally the ICTR has a strong commitment to training the new generation of researchers through comprehensive programs.

Public Health Relevance

; By identifying and overcoming barriers in the translational pathway, increasing scientific collaboration, providing consultative services, clinical infrastructure, and technology cores that bridge the gap between the laboratory and the clinic, the ICTR helps to speed the pace of scientific discovery, and bring effective therapies to the public, and improve the health of Americans.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
2UL1TR000424-06
Application #
8467130
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Brazhnik, Olga
Project Start
2012-09-04
Project End
2013-05-31
Budget Start
2012-09-04
Budget End
2013-05-31
Support Year
6
Fiscal Year
2012
Total Cost
$6,033,752
Indirect Cost
$1,215,398
Name
Johns Hopkins University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Rahman, Mahboob; Hsu, Jesse Yenchih; Desai, Niraj et al. (2018) Central Blood Pressure and Cardiovascular Outcomes in Chronic Kidney Disease. Clin J Am Soc Nephrol 13:585-595
Hardy, Raven; Fani, Negar; Jovanovic, Tanja et al. (2018) Food addiction and substance addiction in women: Common clinical characteristics. Appetite 120:367-373
Chan, Kitty S; Mourtzakis, Marina; Aronson Friedman, Lisa et al. (2018) Upper arm anthropometrics versus DXA scan in survivors of acute respiratory distress syndrome. Eur J Clin Nutr 72:613-617
Li, Yijia; Nouraie, Seyed Mehdi; Kessinger, Cathy et al. (2018) Factors Associated With Progression of Lung Function Abnormalities in HIV-Infected Individuals. J Acquir Immune Defic Syndr 79:501-509
Bundy, Joshua D; Bazzano, Lydia A; Xie, Dawei et al. (2018) Self-Reported Tobacco, Alcohol, and Illicit Drug Use and Progression of Chronic Kidney Disease. Clin J Am Soc Nephrol 13:993-1001
Tipton, Laura; Cuenco, Karen T; Huang, Laurence et al. (2018) Measuring associations between the microbiota and repeated measures of continuous clinical variables using a lasso-penalized generalized linear mixed model. BioData Min 11:12
Maness, Caroline; Saini, Prabhjyot; Bliwise, Donald L et al. (2018) Systemic exertion intolerance disease/chronic fatigue syndrome is common in sleep centre patients with hypersomnolence: A retrospective pilot study. J Sleep Res :e12689
El-Diwany, Ramy; Soliman, Mary; Sugawara, Sho et al. (2018) CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans. Sci Adv 4:eaat0843
Bellin, Melissa H; Newsome, Angelica; Lewis-Land, Cassie et al. (2018) Improving Care of Inner-City Children with Poorly Controlled Asthma: What Mothers Want You to Know. J Pediatr Health Care 32:387-398
Kamdar, Biren B; Sepulveda, Kristin A; Chong, Alexandra et al. (2018) Return to work and lost earnings after acute respiratory distress syndrome: a 5-year prospective, longitudinal study of long-term survivors. Thorax 73:125-133

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