Contact PD/PI: VERBALIS, JOSEPH G PROJECT ABSTRACT The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a primary partnership of Georgetown University (GU) and Howard University (HU), with 3 affiliated hospital systems and research institutes: MedStar Health and Research Institute (MHRI), Oak Ridge National Laboratory (ORNL), and the Washington, DC Veteran's Affairs Medical Center (DCVAMC).
The specific aims of GHUCCTS are: 1) to improve the infrastructure that supports high quality interdisciplinary clinical and translational research, both via inter-institutional collaborations between all GHUCCTS institutions as well as multicenter clinical trials across the national CTSA consortium, with increasing levels of speed and efficiency, and to develop innovative computational methods to speed and enhance translation; 2) to continue to develop GHUCCTS as a model of inter-institutional collaboration that leverages the strengths and attributes of its diverse participating institutions to evolve GHUCCTS into regional CTSA hub with unique and synergistic strengths; 3) to leverage our location, expertise and the co-leadership of a minority-serving institution to design and implement research that will have a high impact on underserved populations with health disparities, including minorities, people with disabilities, and elderly populations; 4) to design and disseminate vibrant and innovative educational programs at multiple levels (undergraduate, medical school, graduate, study coordinators, research nurses, and junior faculty) that promote team science and provides the highest quality of career development training for the clinical and translational investigators of the future; and 5) to both draw from and contribute to the collective efforts of the national CTSA consortium to advance each of the Strategic Goals of GHUCCTS, the National Center for Advancing Translational Science (NCATS), and the CTSA national consortium. The integration of multiple clinical and translational resources across the diverse GHUCCTS institutions will be accompanied by a strong research education, training, and career development program that will train a new generation of clinical and translational researchers. Our innovative approaches to collaboration and interdisciplinary research involving multiple major research-intensive institutions of our region, in collaboration with the national CTSA network, will ensure that our institutions and our community in the Washington, DC area benefit maximally from the generation and application of new discoveries in clinical and translational science. Project Summary/Abstract Page 124 Contact PD/PI: VERBALIS, JOSEPH G

Public Health Relevance

The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a partnership of Georgetown University, Howard University, MedStar Health Research Institute, the Washington DC Veterans Administration Medical Center, and Oak Ridge National Laboratory. Through an innovative collaboration among multiple major research-intensive institutions of our region, GHUCCTS will transform and advance the research and training enterprise in the greater Washington DC region, and will accelerate the translation of scientific discoveries into improved patient care and public health to ensure that our communities in the Washington, DC area benefit maximally from the generation and application of new discoveries in clinical and translational science. Project Narrative Page 125

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
1UL1TR001409-01
Application #
9084738
Study Section
Special Emphasis Panel (ZTR1-SRC (99))
Program Officer
Brazhnik, Olga
Project Start
2015-08-28
Project End
2020-03-31
Budget Start
2015-08-28
Budget End
2016-03-31
Support Year
1
Fiscal Year
2015
Total Cost
$5,238,330
Indirect Cost
$915,749
Name
Georgetown University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Ryu, Rachel J; Easterling, Thomas R; Caritis, Steve N et al. (2018) Prednisone Pharmacokinetics During Pregnancy and Lactation. J Clin Pharmacol 58:1223-1232
Choi, Yongwook; Banerjee, Anirban; McNish, Sean et al. (2018) Co-occurrence of Anaerobes in Human Chronic Wounds. Microb Ecol :
Harris-Love, Michael O; Avila, Nilo A; Adams, Bernadette et al. (2018) The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men. J Clin Med 7:
Lemaitre, Rozenn N; Yu, Chaoyu; Hoofnagle, Andrew et al. (2018) Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study. Diabetes 67:1663-1672
Tominaga, Naoto; Fernandez, Stephen J; Mete, Mihriye et al. (2018) Hyponatremia and the risk of kidney stones: A matched case-control study in a large U.S. health system. PLoS One 13:e0203942
Kheirbek, Raya Elfadel; Fokar, Ali; Moore, Hans J et al. (2018) Association between lifetime risk of atrial fibrillation and mortality in the oldest old. Clin Cardiol 41:634-639
Wexler, Deborah J; Powe, Camille E; Barbour, Linda A et al. (2018) Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Obstet Gynecol 132:496-505
Wicker, Evan; Turchi, Janita; Malkova, Ludise et al. (2018) Mediodorsal thalamus is required for discrete phases of goal-directed behavior in macaques. Elife 7:
Suskin, Zaev D; Giordano, James J (2018) Body -to-head transplant; a ""caputal"" crime? Examining the corpus of ethical and legal issues. Philos Ethics Humanit Med 13:10
Desai, Pinkal; Wallace, Robert; Anderson, Matthew L et al. (2018) An analysis of the association between statin use and risk of endometrial and ovarian cancers in the Women's Health Initiative. Gynecol Oncol 148:540-546

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