The mission of the Northwestern University Clinical and Translational Sciences (NUCATS) Institute is ?speeding transformative research discoveries to patients and the population.? The NUCATS Institute, founded in 2007, serves as the hub for clinical and translational research across Northwestern University, its renowned clinical partners (Northwestern Memorial HealthCare, Ann & Robert H. Lurie Children's Hospital of Chicago, and the Rehabilitation Institution of Chicago), community and stakeholder organizations, patients, and industry. In this funding period, NUCATS will continue to support the entire spectrum of translation ? from basic discovery through clinical trials to population health research ? regardless of disease area. We will build upon our past accomplishments and current strengths to undertake new initiatives that address challenges and opportunities in clinical and translational science. We will pursue the following Global Aims, which are aligned with NCATS' goals for the CTSA program: 1) We will further integrate research into clinical care systems and processes, with the goal that every clinical encounter becomes an opportunity for research and learning to improve human health; 2) We will innovate, test, and disseminate new education and training initiatives to equip the translational workforce and improve quality and efficiency of translational research; 3) We will build upon our expertise in the science of team science and create practical tools that catalyze and empower high-functioning, stakeholder- engaged, multi-disciplinary teams; and 4) We will take an experimental approach to improve the methods and processes of translational research and create a culture of continuous improvement that can be disseminated across the CTSA consortium. Continued CTSA funding will be a critical element, speeding the design, demonstration, and dissemination of innovative and generalizable solutions for translational science and advancing our commitment to improved human health. Project Summary/Abstract Page 251 Contact PD/PI: LLOYD-JONES, DONALD M

Public Health Relevance

The mission of the Northwestern University Clinical and Translational Sciences (NUCATS) Institute is ?speeding transformative research discoveries to patients and the population.? The NUCATS Institute serves as the hub for clinical and translational research across Northwestern University and its clinical partners, Northwestern Memorial HealthCare, Ann & Robert H. Lurie Children's Hospital of Chicago, and the Rehabilitation Institution of Chicago. In this funding period, NUCATS will build on its unique strengths to integrate research into all aspects of clinical care, train and equip the translational workforce, build and support multi-disciplinary teams that include community stakeholders, and the evaluation and continuous improvement of methods and processes to enhance clinical and translational research. Project Narrative Page 252

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
1UL1TR001422-01
Application #
9085559
Study Section
Special Emphasis Panel (ZTR1-SRC (99))
Program Officer
Wilde, David B
Project Start
2015-08-12
Project End
2019-03-31
Budget Start
2015-08-12
Budget End
2016-03-31
Support Year
1
Fiscal Year
2015
Total Cost
$5,470,353
Indirect Cost
$1,799,598
Name
Northwestern University at Chicago
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Ibler, E; Tran, G; Orrell, K A et al. (2018) Inverse association for diagnosis of Alzheimer's disease subsequent to both melanoma and non-melanoma skin cancers in a large, urban, single-centre, Midwestern US patient population. J Eur Acad Dermatol Venereol 32:1893-1896
Aaron, Carrie P; Schwartz, Joseph E; Hoffman, Eric A et al. (2018) A Longitudinal Cohort Study of Aspirin Use and Progression of Emphysema-like Lung Characteristics on CT Imaging: The MESA Lung Study. Chest 154:41-50
Liotta, Eric Michael; Romanova, Anna L; Lizza, Bryan D et al. (2018) Osmotic Shifts, Cerebral Edema, and Neurologic Deterioration in Severe Hepatic Encephalopathy. Crit Care Med 46:280-289
Zhang, Angelica; Veesenmeyer, Jeffrey L; Hauser, Alan R (2018) Phosphatidylinositol 4,5-Bisphosphate-Dependent Oligomerization of the Pseudomonas aeruginosa Cytotoxin ExoU. Infect Immun 86:
Garcia, Julio; van der Palen, Roel L F; Bollache, Emilie et al. (2018) Distribution of blood flow velocity in the normal aorta: Effect of age and gender. J Magn Reson Imaging 47:487-498
Cameron, Anne P; Lewicky-Gaupp, Christina; Smith, Abigail R et al. (2018) Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study. J Urol 199:1023-1031
Puckett, Jae A; Feinstein, Brian A; Newcomb, Michael E et al. (2018) Trajectories of Internalized Heterosexism among Young Men Who have Sex with Men. J Youth Adolesc 47:872-889
Gilbert, Abigail L; Lee, Jungwha; Song, Jing et al. (2018) Relationship Between Self-Reported Restless Sleep and Objectively Measured Physical Activity in Adults With Knee Osteoarthritis. Arthritis Care Res (Hoboken) :
Malik, Kunal; He, Helen; Huynh, Thy Nhat et al. (2018) Ichthyosis molecular fingerprinting shows profound Th17-skewing and a unique barrier genomic signature. J Allergy Clin Immunol :
Akhabue, Ehimare; Perak, Amanda M; Chan, Cheeling et al. (2018) Racial Differences in Rates of Change of Childhood Body Mass Index and Blood Pressure Percentiles. J Pediatr 202:98-105.e6

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