The Michigan Institute for Clinical & Health Research (MICHR) is a catalytic hub that significantly impacts the translation of investigative science into innovative improvements in clinical care and health policy. Our objective is to empower researchers and research communities within and outside the University of Michigan (U-M), creating a positive impact on health across local, regional, national, and global scales. We will achieve this objective through the following overarching specific aims: 1) Innovate and implement effective educational approaches to developing a skilled and diverse translational research workforce; 2) Catalyze effective research with community partnerships to accelerate the translation of breakthroughs that benefit society; 3) Promote clinical and translational research across translational phases and across the lifespan; 4) Advance research methods and processes that enable higher quality clinical and translational research; 5) Develop, demonstrate, and disseminate informatics innovations that facilitate the translation of biomedical discoveries to health impact. MICHR aspires to have a unique, substantial, measurable, and recognizable impact on U-M and the health of our communities. In order to achieve this with efficiency, we have critically evaluated pre- existing strengths and emerging opportunities across the institutional research landscape. MICHR will enhance and develop partnerships with major research and regulatory units on campus to develop an efficient pipeline that accelerates the translation and implementation of discoveries while also promoting cross-cutting signature initiatives that engage research and community members from all phases of translation.

Public Health Relevance

The Michigan Institute for Clinical & Health Research (MICHR) is a catalytic hub that significantly impacts the translation of investigative science into innovative improvements in clinical care and health policy. Our objective is to empower researchers and research communities within and outside the University of Michigan, creating a positive impact on health across local, regional, national, and global scales. MICHR will build on a decade of enabling and enhancing clinical and translational research. We expect expanded positive impact as we develop, demonstrate, and disseminate innovative and highly integrated initiatives across our institute, the University of Michigan campus, surrounding communities, and the Clinical Translational Science Awards consortium.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR002240-05
Application #
10116514
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Chang, Soju
Project Start
2017-06-01
Project End
2022-02-28
Budget Start
2021-03-01
Budget End
2022-02-28
Support Year
5
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Zheng, Fang; Dang, Jianzhong; Zhang, Hongyu et al. (2018) Cancer Stem Cell Vaccination With PD-L1 and CTLA-4 Blockades Enhances the Eradication of Melanoma Stem Cells in a Mouse Tumor Model. J Immunother 41:361-368
Carlozzi, Noelle E; Kallen, Michael A; Ianni, Phillip A et al. (2018) The development of a two new computer adaptive tests to evaluate feelings of loss in caregivers of individuals with traumatic brain injury: TBI-CareQOL Feelings of Loss-Self and Feelings of Loss-Person with Traumatic Brain Injury. Arch Phys Med Rehabil :
Tang, Ming; Gao, Chao; Goutman, Stephen A et al. (2018) Model-Based and Model-Free Techniques for Amyotrophic Lateral Sclerosis Diagnostic Prediction and Patient Clustering. Neuroinformatics :
Carlozzi, Noelle E; Hanks, Robin; Lange, Rael T et al. (2018) Understanding Health-related Quality of Life in Caregivers of Civilians and Service Members/Veterans With Traumatic Brain Injury: Establishing the Reliability and Validity of PROMIS Mental Health Measures. Arch Phys Med Rehabil :
Johnson, Alexa K; Palmieri-Smith, Riann M; Lepley, Lindsey K (2018) Contribution of Neuromuscular Factors to Quadriceps Asymmetry After Anterior Cruciate Ligament Reconstruction. J Athl Train 53:347-354
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Cohen, Ezra M; Edwards, Robert R; Bingham 3rd, Clifton O et al. (2018) Pain and Catastrophizing in Patients With Rheumatoid Arthritis: A Prospective Observational Cohort Study. J Clin Rheumatol :
Hoffman, Geoffrey J; Ha, Jinkyung; Alexander, Neil B et al. (2018) Underreporting of Fall Injuries of Older Adults: Implications for Wellness Visit Fall Risk Screening. J Am Geriatr Soc 66:1195-1200
Carlozzi, Noelle E; Sherman, Carey W; Angers, Kaley et al. (2018) Caring for an individual with mild cognitive impairment: a qualitative perspective of health-related quality of life from caregivers. Aging Ment Health 22:1190-1198
Tank, E M; Figueroa-Romero, C; Hinder, L M et al. (2018) Abnormal RNA stability in amyotrophic lateral sclerosis. Nat Commun 9:2845

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