The LPD in cooperation with scientist at the National School of Medicine of Mali have developed a Malaria Research and Training Center in Bamako. The goals of the MRTC are several. First is to nurture a center of research excellence in Africa where the work is planned, directed and executed primarily by African scientists. In cooperation with scientists from more developed countries, research is aimed at producing strategies for the control of malaria in Africa using the most modern and appropriate technologies. To facilitate these studies, laboratories have been renovated and equipped. A major training program has been initiated for Malian staff members to provide expertise in all areas of biology, tropical medicine and epidemiology with emphasis on molecular biology and immunology. A second goal is to provide a facility in a malaria endemic area where the results of laboratory studies at the NIH and in other laboratories can be readily tested and applied to studies of malaria in the field. Most important will be the relationship between the MRTC and the newly formed Malaria Vaccine Development Unit of the LPD. The Center in Mali is being expanded to serve as the major site for testing malaria vaccine candidates being developed at the NIH.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Intramural Research (Z01)
Project #
1Z01AI000629-07
Application #
6098994
Study Section
Special Emphasis Panel (LPD)
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1998
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code
Manoukis, Nicholas C; Diabate, Abdoulaye; Abdoulaye, Adamou et al. (2009) Structure and dynamics of male swarms of Anopheles gambiae. J Med Entomol 46:227-35
Diabate, Abdoulaye; Dao, Adama; Yaro, Alpha S et al. (2009) Spatial swarm segregation and reproductive isolation between the molecular forms of Anopheles gambiae. Proc Biol Sci 276:4215-22
Lehmann, Tovi; Hume, Jen C C; Licht, Monica et al. (2009) Molecular evolution of immune genes in the malaria mosquito Anopheles gambiae. PLoS One 4:e4549
Sogoba, Nafomon; Doumbia, Seydou; Vounatsou, Penelope et al. (2007) Monitoring of larval habitats and mosquito densities in the Sudan savanna of Mali: implications for malaria vector control. Am J Trop Med Hyg 77:82-8
Diabate, Abdoulaye; Dabire, Roch K; Millogo, Niama et al. (2007) Evaluating the effect of postmating isolation between molecular forms of Anopheles gambiae (Diptera: Culicidae). J Med Entomol 44:60-4
Simard, Frederic; Licht, Monica; Besansky, Nora J et al. (2007) Polymorphism at the defensin gene in the Anopheles gambiae complex: testing different selection hypotheses. Infect Genet Evol 7:285-92
Yaro, A S; Dao, A; Adamou, A et al. (2006) Reproductive output of female Anopheles gambiae (Diptera: Culicidae): comparison of molecular forms. J Med Entomol 43:833-9
Marcet, P L; Lehmann, T; Groner, G et al. (2006) Identification and characterization of microsatellite markers in the Chagas disease vector Triatoma infestans (Heteroptera: Reduviidae). Infect Genet Evol 6:32-7
Diabate, Abdoulaye; Dabire, Roch K; Kengne, Pierre et al. (2006) Mixed swarms of the molecular M and S forms of Anopheles gambiae (Diptera: Culicidae) in sympatric area from Burkina Faso. J Med Entomol 43:480-3
Lehmann, Tovi; Dalton, Ryan; Kim, Eun Hea et al. (2006) Genetic contribution to variation in larval development time, adult size, and longevity of starved adults of Anopheles gambiae. Infect Genet Evol 6:410-6

Showing the most recent 10 out of 16 publications