Research activities supported this year through the CDS include:? 1. NIAMS Summer Internship Program? 2. Advising of All Trainees (Postdoc/Postbac/Grad/Medical/Summer)? 3. Fellows' Training/Individual Career Development/Group Workshops/Classes? - CV/Resume Writing? - Career Counseling? - Spoken English Courses? - Scientific Writing Courses? - Grant Writing Courses? - Networking? 4. University Course Teaching Opportunities (Postdoc Skill Development)? - Course/Syllabus Planning and Design? - Lecture Planning? - Logistics and Coordination? - Liaison with Universities? 5. Answer internal and public inquiries to provide help in finding/placing Trainees/Fellows? 6. Emergency Management/Continuity of Operations Planning (EM/COOP)? 7. Administering NIH Loan Repayment Program for NIAMS Fellows? 8. NIH Public Access Policy Oversight? 9. NIAMS Internet and Intranet Content Management and Official Posting Source? 10. Technology Transfer Development/Coordination/Education? 11. Oversight of Mandatory Annual Biomedical Research Ethics Training? 12. Intramural Retreat Planning and Organization? 13. Manuscript Transmittal Oversight? 14. Space Management Support? 15. IRP Scientific Seminar Series (Planning and Coordination)? 16. SharePoint Pilot Project Contribution (Knowledge Management)? 17. Outreach/Recruitment:? - National Graduate Student Research Festival (Planning Committee) ? - NIH Community College Summer Semester (Creation and Development) ? - Administer Work Force Recruitment Program (Disability Employment)? - Operation Warfighter/NIH Warrior Transition Program (Scientific Coordinator)? - Police Activities League of Montgomery County (NIAMS initiative)? - Adopt-a-School Partnerships (NIAMS specific)? - Support of Local Science Fairs (Workshops/Judging)? 18. Participation at National Conferences to Promote Diversity in Biomedical Research Careers? - Society for the Advancement of Chicanos and Native Americans in Science (SACNAS)? - Annual Biomedical Research Conference for Minority Students (ABRCMS)? - American Indian Science and Engineering Society (AISES)? - Road to Recovery Conference (Department of Defense)? 19. Hosting Students from National Youth Initiatives and Other Non-Profit Organizations (NIH-wide)? - National Native American Youth Initiative? - National Hispanic Youth Initiative? - National African American Youth Initiative? - Jeter's Leaders Youth Development Program? 20. NIAMS Representation on NIH Hispanic Employee Committee? 21. NIAMS Liaison for the Office of Equal Opportunity and Diversity Management (OEODM)? 22. Monitor and Report NIAMS Training Contribution to the NIH Most Efficient Organization (MEO)? 23. Prepare Government Accountability Office (GAO) Response for NIAMS? 24. Prepare and Monitor NIAMS Management Directive-715 (Equal Employment Opportunity)? 25. Prepare EEO Updates for Inclusion in the Shorttakes (NIAMS Council)? 26. NIAMS Coordinator for National Take Your Child to Work Day at NIH? ? Specific areas of research training supported by the CDS include:? - Elucidation of the structure and function of the cellular receptor for IgE? - Studies into the mechanisms of cytokine signal transduction? - Identification of Jak3 mutations as one of the major causes of severe combined immunodeficiency? - Development of Jak3 antagonists as a potential new class of immunosuppressive drugs? - Establishment of one of the worlds largest cohorts of patients with inflammatory myopathy, which has provided the basis for ground- breaking studies on the natural history, pathogenesis, and treatment of polymyositis and dermatomyositis, recognition of a new category of illness, the systemic autoinflammatory diseases? - Discovery of several of the causative genes, including the genes mutated in familial Mediterranean fever (FMF)? - Insight into TNF receptor- associated periodic syndrome (TRAPS), and the neonatal-onset multisystem inflammatory disease (NOMID)? - Discovery of the genes causing a number of Mendelian disorders of the skin? - Elucidation of the structure and assembly of several viruses, including members of the Herpes family, hepatitis B, and HIV? - Providing new insights into the structure of amyloid fibrils, prions, and cytoskeletal filaments? - Examination into the role of MyoD in muscle gene expression
