This study is designed to assess and evaluate the ototoxic effects of cis platinum therapy in this patient population. Patients are also receiving audiologic rehabilitation intervention in the form of referrals for hearing aid fitting and counseling as indicated on a patient-by-patient basis. Audiologic data in this group of patients are being compiled re: high frequency hearing, recognition for speech in quiet and recognition for speech in ipsilateral noise condition (+5 dB signal-to-noise ratio). Patients are followed audiologically with each cycle of cis platinum. Ototoxic effects will also be studied in consideration of method, rate and amount of cis platinum administrations. As of 1 May 1985, 138 patients have been seen. Audiologic data are regularly provided to Dr. R.C. Young in Medicine Branch.

Agency
National Institute of Health (NIH)
Institute
Clinical Center (CLC)
Type
Intramural Research (Z01)
Project #
1Z01CL007005-02
Application #
4692003
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Clinical Center
Department
Type
DUNS #
City
State
Country
United States
Zip Code