The two major themes in this project involve transport in disordered media and the development of models for reaction kinetics in chemistry. In addition to work on these, some time was spent on the calculation of the dependence of the relaxation time for the transition from elastic viscosity to plastic viscosity behavior of a polymer on the molecular weight. Together with S. Havlin and R. Kopelman we have investigated the spatial distribution of reactants in one and three dimensions. In one dimension the kinetic properties do not follow classical laws while in three dimensions they do. We show that these effects are due in part to the non-Poisson spatial distribution of reactants in one dimension. Measurements of the dependence of the relaxation time polymer viscosity on the molecular weight deviate from the theoretical prediction that such dependence should go as the inverse third power. Experiments are consistent with the dependence on a power that ranges between -3.3 and -4. Together with J. Bendler, M. Dishon, and H. Kesten we have produced a physical model in which the indicated power is -10/3 which is in much better agreement with the experimental data than earlier theoretical work.

Agency
National Institute of Health (NIH)
Institute
Center for Information Technology (CIT)
Type
Intramural Research (Z01)
Project #
1Z01CT000024-13
Application #
3916951
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Computer Research and Technology
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Shvartsman, Stanislav Y; Coppey, Mathieu; Berezhkovskii, Alexander M (2008) Dynamics of maternal morphogen gradients in Drosophila. Curr Opin Genet Dev 18:342-7
Vazquez, Marco-Vinicio; Berezhkovskii, Alexander M; Dagdug, Leonardo (2008) Diffusion in linear porous media with periodic entropy barriers: A tube formed by contacting spheres. J Chem Phys 129:046101
Berezhkovskii, Alexander M; Bezrukov, Sergey M (2008) Fluctuation theorem for channel-facilitated membrane transport of interacting and noninteracting solutes. J Phys Chem B 112:6228-32
Berezhkovskii, Alexander M; Weiss, George H (2008) Propagators and related descriptors for non-Markovian asymmetric random walks with and without boundaries. J Chem Phys 128:044914
Berezhkovskii, Alexander M; Bezrukov, Sergey M (2008) Counting translocations of strongly repelling particles through single channels: fluctuation theorem for membrane transport. Phys Rev Lett 100:038104
Coppey, Mathieu; Boettiger, Alistair N; Berezhkovskii, Alexander M et al. (2008) Nuclear trapping shapes the terminal gradient in the Drosophila embryo. Curr Biol 18:915-9
Bezrukov, Sergey M; Berezhkovskii, Alexander M; Szabo, Attila (2007) Diffusion model of solute dynamics in a membrane channel: mapping onto the two-site model and optimizing the flux. J Chem Phys 127:115101
Dagdug, Leonardo; Berezhkovskii, Alexander M; Makhnovskii, Yurii A et al. (2007) Transient diffusion in a tube with dead ends. J Chem Phys 127:224712
Berezhkovskii, A M; Pustovoit, M A; Bezrukov, S M (2007) Diffusion in a tube of varying cross section: numerical study of reduction to effective one-dimensional description. J Chem Phys 126:134706
Berezhkovskii, A M; Barzykin, A V (2007) Simple formulas for the trapping rate by nonspherical absorber and capacitance of nonspherical conductor. J Chem Phys 126:106102

Showing the most recent 10 out of 32 publications