The purpose of this project is to continue assess the neuropsychiatric status of HIV-positive individuals who have abused drugs over a long period of their lives. This protocol includes 60 HIV positive participants who do not show any overt signs or symptoms related to AIDS. Data collected from the HIV positive individuals are being compared to seronegative individuals with similar drug history. Preliminary analyses suggest that HIV-positive individuals have greater asymmetry than HIV-negative subjects on EEG and blood flow. The blood flow data are the first such demonstration while the EEG data replicate those of others.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Intramural Research (Z01)
Project #
1Z01DA000174-04
Application #
6103874
Study Section
Special Emphasis Panel (CNRB)
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1998
Total Cost
Indirect Cost
Name
National Institute on Drug Abuse
Department
Type
DUNS #
City
State
Country
United States
Zip Code
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Cadet, Jean Lud; Jayanthi, Subramaniam; Deng, Xiaolin (2003) Speed kills: cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis. FASEB J 17:1775-88

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