This project assesses methods for decreasing HIV-risk behaviors in substance abusers, and assesses the safety and efficacy of pharmacological and behavioral treatments for opioid dependence in those already infected with HIV. A randomized clinical trial examined whether sustained HIV-protective behaviors can be achieved by adding a cognitive-behavioral coping-skills and relapse-prevention intervention to voucher-based contingency management has been completed. Inner-city methadone-maintained cocaine abusers were taught: 1) to identify and seek out sources of reinforcement that do not carry risks of HIV; and 2) to develop adaptive problem-focused and emotion-focused coping responses to general and drug-specific stressors that might otherwise trigger HIV-risk behaviors. Data are being analyzed.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Intramural Research (Z01)
Project #
1Z01DA000231-07
Application #
6431932
Study Section
(CPTB)
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
2000
Total Cost
Indirect Cost
Name
National Institute on Drug Abuse
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Edwards, Ellen P; Homish, Gregory G; Eiden, Rina D et al. (2009) Longitudinal prediction of early childhood discipline styles among heavy drinking parents. Addict Behav 34:100-6
Kachadourian, Lorig K; Eiden, Rina D; Leonard, Kenneth E (2009) Paternal alcoholism, negative parenting, and the mediating role of marital satisfaction. Addict Behav 34:918-27
Willner-Reid, Jessica; Belendiuk, Katherine A; Epstein, David H et al. (2008) Hepatitis C and human immunodeficiency virus risk behaviors in polydrug users on methadone maintenance. J Subst Abuse Treat 35:78-86
Ghitza, Udi E; Epstein, David H; Preston, Kenzie L (2008) Contingency management reduces injection-related HIV risk behaviors in heroin and cocaine using outpatients. Addict Behav 33:593-604
Schroeder, Jennifer R; Epstein, David H; Umbricht, Annie et al. (2006) Changes in HIV risk behaviors among patients receiving combined pharmacological and behavioral interventions for heroin and cocaine dependence. Addict Behav 31:868-79
Boyd, Susan J; Thomas-Gosain, Neena F; Umbricht, Annie et al. (2004) Gender differences in indices of opioid dependency and medical comorbidity in a population of hospitalized HIV-infected African-Americans. Am J Addict 13:281-91
Umbricht, Annie; Hoover, Donald R; Tucker, Marvin J et al. (2003) Opioid detoxification with buprenorphine, clonidine, or methadone in hospitalized heroin-dependent patients with HIV infection. Drug Alcohol Depend 69:263-72
Preston, Kenzie L; Umbricht, Annie; Epstein, David H (2002) Abstinence reinforcement maintenance contingency and one-year follow-up. Drug Alcohol Depend 67:125-37
Preston, K L; Umbricht, A; Wong, C J et al. (2001) Shaping cocaine abstinence by successive approximation. J Consult Clin Psychol 69:643-54
Preston, K L; Umbricht, A; Epstein, D H (2000) Methadone dose increase and abstinence reinforcement for treatment of continued heroin use during methadone maintenance. Arch Gen Psychiatry 57:395-404