Secretory and endocytic processes in several cell types are currently under investigation. Cell dissociation and short term culture (up to 1 month) methods have been established for rat exorbital lacrimal, parotid and pancreatic acinar cells. These cultures are being used to study various aspects of the secretory process. Emphasis is placed on morphological, cytochemical and biochemical characterization of the cultured cells. Uptake and fate of both soluble phase and membrane bound markers by cultured cells are being examined in vivo and in vitro. The lysosomal system and its role in endocytic processes is also under study.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Intramural Research (Z01)
Project #
1Z01DE000199-10
Application #
3963700
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Dental & Craniofacial Research
Department
Type
DUNS #
City
State
Country
United States
Zip Code