Abstract

Studies involving patients with islet cell tumors (Zollinger Ellison syndrome, insulinoma, VIPoma) are directed to further understanding the pathogenesis of the syndromes and to developing alternative, more effective modes of therapy utilizing both medical and surgical approaches.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Intramural Research (Z01)
Project #
1Z01DK053200-01
Application #
3876435
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
National Institute of Diabetes and Digestive and Kidney Diseases
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Metz, David C; Cadiot, Guillaume; Poitras, Pierre et al. (2017) Diagnosis of Zollinger-Ellison syndrome in the era of PPIs, faulty gastrin assays, sensitive imaging and limited access to acid secretory testing. Int J Endocr Oncol 4:167-185
Ito, Tetsuhide; Igarashi, Hisato; Uehara, Hirotsugu et al. (2013) Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with 1613 literature MEN1 patients with or without pancreatic endocrine tumors. Medicine (Baltimore) 92:135-81
Metz, David C; Jensen, Robert T (2008) Gastrointestinal Neuroendocrine Tumors: Pancreatic Endocrine Tumors. Gastroenterology :
Norton, Jeffrey A; Venzon, David J; Berna, Marc J et al. (2008) Prospective study of surgery for primary hyperparathyroidism (HPT) in multiple endocrine neoplasia-type 1 and Zollinger-Ellison syndrome: long-term outcome of a more virulent form of HPT. Ann Surg 247:501-10
Long, Scott H; Berna, Marc J; Thill, Michelle et al. (2007) Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. J Clin Endocrinol Metab 92:4394-402
Norton, Jeffrey A; Jensen, Robert T (2007) Role of surgery in Zollinger-Ellison syndrome. J Am Coll Surg 205:S34-7
Berna, Marc J; Hoffmann, K Martin; Serrano, Jose et al. (2006) Serum gastrin in Zollinger-Ellison syndrome: I. Prospective study of fasting serum gastrin in 309 patients from the National Institutes of Health and comparison with 2229 cases from the literature. Medicine (Baltimore) 85:295-330
Norton, Jeffrey A; Fang, Tony D; Jensen, Robert T (2006) Surgery for gastrinoma and insulinoma in multiple endocrine neoplasia type 1. J Natl Compr Canc Netw 4:148-53
Jensen, Robert T (2006) Pancreatic neuroendocrine tumors: overview of recent advances and diagnosis. J Gastrointest Surg 10:324-6
Berna, Marc J; Hoffmann, K Martin; Long, Scott H et al. (2006) Serum gastrin in Zollinger-Ellison syndrome: II. Prospective study of gastrin provocative testing in 293 patients from the National Institutes of Health and comparison with 537 cases from the literature. evaluation of diagnostic criteria, proposal of new Medicine (Baltimore) 85:331-64

Showing the most recent 10 out of 35 publications